Table 4 GO analysis by GSEA
From: Ubiquitin-specific protease as the underlying gene biomarker for aortic stenosis
TERM | SIZE | NES | p-val | RANK AT MAX | LEADING EDGE |
|---|---|---|---|---|---|
Up-regulated | |||||
GO_REGULATION_OF_CARDIAC_MUSCLE_CELL_CONTRACTION | 18 | −1.67584 | 0.003914 | 1264 | tags = 61%, list = 19%, signal = 75% |
GO_HEART_PROCESS | 36 | −1.50175 | 0.037109 | 1395 | tags = 42%, list = 21%, signal = 52% |
GO_PROTEIN_KINASE_A_BINDING | 17 | −1.51351 | 0.019841 | 977 | tags = 47%, list = 14%, signal = 55% |
GO_ENDOCARDIAL_CUSHION_DEVELOPMENT | 21 | −1.55367 | 0.009862 | 1768 | tags = 52%, list = 26%, signal = 71% |
GO_STRUCTURAL_CONSTITUENT_OF_CYTOSKELETON | 42 | −1.6003 | 0.00996 | 1034 | tags = 40%, list = 15%, signal = 48% |
Down-regulated | |||||
GO_MULTICELLULAR_ORGANISMAL_MACROMOLECULE_METABOLIC_PROCESS | 43 | 1.747944 | 0.012146 | 679 | tags = 51%, list = 10%, signal = 57% |
GO_MULTICELLULAR_ORGANISM_METABOLIC_PROCESS | 47 | 1.695392 | 0.014344 | 679 | tags = 47%, list = 10%, signal = 52% |
GO_CELL_CHEMOTAXIS | 76 | 1.53365 | 0.031955 | 1128 | tags = 53%, list = 17%, signal = 62% |
GO_REGULATION_OF_BONE_REMODELING | 18 | 1.481831 | 0.01145 | 916 | tags = 50%, list = 14%, signal = 58% |
GO_REGULATION_OF_STEROL_TRANSPORT | 15 | 1.481576 | 0.059289 | 1346 | tags = 53%, list = 20%, signal = 66% |