Table 5 KEGG analysis by GSEA
From: Ubiquitin-specific protease as the underlying gene biomarker for aortic stenosis
TERM | SIZE | NES | p-val | RANK AT MAX | LEADING EDGE |
|---|---|---|---|---|---|
Up-regulated | |||||
KEGG_ARRHYTHMOGENIC_RIGHT_VENTRICULAR_CARDIOMYOPATHY_ARVC | 40 | −1.38995 | 0.071984 | 1598 | tags = 43%, list = 24%, signal = 55% |
KEGG_PEROXISOME | 37 | −1.21825 | 0.236686 | 1355 | tags = 43%, list = 20%, signal = 54% |
KEGG_PEROXISOME | 37 | −1.21825 | 0.236686 | 1355 | tags = 43%, list = 20%, signal = 54% |
KEGG_GAP_JUNCTION | 50 | −1.20703 | 0.208333 | 1746 | tags = 44%, list = 26%, signal = 59% |
KEGG_CALCIUM_SIGNALING_PATHWAY | 67 | −1.12748 | 0.296813 | 1585 | tags = 36%, list = 23%, signal = 46% |
Down-regulated | |||||
KEGG_CARDIAC_MUSCLE_CONTRACTION | 32 | 1.191075 | 0.318271 | 1839 | tags = 66%, list = 27%, signal = 90% |
KEGG_CYTOKINE_CYTOKINE_RECEPTOR_INTERACTION | 94 | 1.251404 | 0.201942 | 1695 | tags = 55%, list = 25%, signal = 73% |
KEGG_GLUTATHIONE_METABOLISM | 23 | 1.371425 | 0.064327 | 1499 | tags = 61%, list = 22%, signal = 78% |
KEGG_OXIDATIVE_PHOSPHORYLATION | 76 | 1.331254 | 0.211045 | 1839 | tags = 70%, list = 27%, signal = 95% |
KEGG_CELL_ADHESION_MOLECULES_CAMS | 64 | 1.131856 | 0.316602 | 1047 | tags = 39%, list = 16%, signal = 46% |