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Table 3 Effect estimates of the selected path analysis model (via stepwise regression)

From: A structural equation model to assess the pathways of body adiposity and inflammation status on dysmetabolic biomarkers via red cell distribution width and mean corpuscular volume: a cross-sectional study in overweight and obese subjects

 

Estimate (β)

Standardized

Estimate (β)*

P (|Z| > z)

95% CI

Direct effect retained by model selection

 BMI → CRP

0.048

0.328

0.001

0.019; 0.078

 BMI → ROS

0.233

0.136

0.049

0.001; 0.465

 BMI → RDW

−0.138

− 0.241

0.012

− 0.247; − 0.030

 WC → Lag-time (a)

− 0.365

− 0.198

< 0.001

− 0.549; − 0.180

 WC → RDW

0.123

0.646

< 0.001

0.091; 0.156

 CRP → RDW

0.292

0.075

0.101

−0.057; 0.642

 CRP → MCV

−1.546

−0.205

< 0.001

− 2.317; − 0.775

 ROS → Slope

0.011

0.243

0.010

0.003; 0.020

 ROS → Lag-time

−1.278

−0.396

< 0.001

− 1.860; − 0.696

 RDW → HOMA

0.086

0.179

0.010

0.021; 0.151

 RDW → HDL

−0.038

− 0.196

0.006

−0.065; − 0.011

 RDW → BGL

0.042

0.094

0.074

−0.004; 0.089

 RDW → Insulin

0.343

0.165

0.020

0.055; 0.631

 MCV → HDL

0.011

0.113

0.105

−0.002; 0.025

 MCV → Insulin

−0.036

−0.033

0.003

−0.060; − 0.012

(main) indirect effect

 BMI → CRP → MCV

− 0.075

−0.067

0.012

−0.133; − 0.016

 BMI → ROS → Lag-time

−0.298

− 0.054

0.070

− 0.620; 0.024

 BMI → RDW → HOMA

−0.012

− 0.043

0.056

− 0.024; 0.000

 BMI → RDW → HDL

0.005

0.047

0.050

0.000; 0.010

 BMI → RDW → Insulin

−0.047

−0.040

0.069

−0.098; 0.004

 WC → RDW → HOMA

0.011

0.116

0.013

0.002; 0.019

 WC → RDW → HDL

−0.005

−0.126

0.010

−0.008; − 0.001

 WC → RDW → BGL

0.005

0.061

0.084

−0.001; 0.011

 WC → RDW → Insulin

0.042

0.107

0.024

0.005; 0.079

 CRP → MCV → Insulin

0.055

0.007

0.015

0.011; 0.100

  1. In bold: P < 0.05; in italic: 0.05 ≤ P < 0.10
  2. Goodness of fit indexes: chi-square = 88.839 (P < 0.001), baseline chi-square = 932.538 (P < 0.001), SRMR = 0.104, RMSEA = 0.084 (90%CI = 0.061; 0.107), CFI = 0.944, TLI = 0.906
  3. (a) discovered by the modification indexes
  4. → = effect, BMI = Body Mass Index, CRP = C-Reactive Protein, ROS = Reactive Oxygen Species, RDW = Red Cell Distribution Width, MCV = Mean Corpuscular Volume, WC = Waist Circumference, HOMA = Homeostasis Model Assessment, HDL = high-density lipoprotein cholesterol, BGL = Blood Glucose Level
  5. *Since the variables are measured on various scales, standardized estimates (β*) rather than raw effects (β) are shown using the standard deviations as measurement units for the variables. Therefore, these are standardized partial regression coefficients are effects of explanatory variable on response variable, controlling for the other variables of the model