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Fig. 5 | Lipids in Health and Disease

Fig. 5

From: Ethanol-mediated upregulation of APOA1 gene expression in HepG2 cells is independent of de novo lipid biosynthesis

Fig. 5

Effects of ethanol on expression of genes involve in the cholesterol biosynthesis pathway. RNA levels of the indicated genes were determined by RT-qPCR as described in Methods. a, bAPOC3 and APOA4 RNA levels were compared between cell types HepG2 and Caco-2 respectively, treated with the indicated final concentrations of ethanol. c, dAPOC3, APOA4 and APOB gene expression were compared between standard medium (FBS) and lipid-depleted medium (LPDS), treated with the indicated concentrations of ethanol and/or atorvastatin. The error bars represent the SD from the mean of five assays of an individual experiment. *Significant difference, ethanol treatment versus untreated control (1 way ANOVA with multiple comparisons; n = 5; *P < 0.05, **P < 0.01, ***P < 0.001 vs. control)

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Lipids in Health and Disease

ISSN: 1476-511X