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Table 1 Characteristics* of participants by quintile of the lipoprotein insulin resistance score (n = 980)

From: A lipidome-wide association study of the lipoprotein insulin resistance index

CharacteristicsQ1 (n = 198)Q2 (n = 200)Q3(n = 194)Q4(n = 199)Q5 (n = 184)P-value
Age at blood draw (y)45.0 (35.0–75.5)46.0 (34.0–61.3)48.0 (39.3–61.8)50.0 (40.5–63.0)49.5 (40.0–61.3)0.008
Sex
 Male43 (22)82 (41)110 (57)106 (53)125 (68)<  0.001
BMI (kg/m2)23.9 (21.6–27.4)25.6 (23.0–28.9)27.8 (25.5–30.9)29.4 (27.0–32.5)31.0 (27.8–33.8)<  0.001
Waist circumference (cm)
 Male88.0 (83.0–93.5)93.5 (89.0–100.0)98.0 (91.0–105.0)103.0 (97.0–111.0)105.0 (97.0–113.0)<  0.001
 Female80.0 (74.0–89.5)86.0 (79.0–94.0)94.5 (85.8–105.3)100.0 (91.0–110.0)109.0 (96.5–118.0)<  0.001
Fasting glucose (mg/dl)92.0 (89.0–98.0)94.0 (90.0–101.0)97.5 (93.0–105.0)101.0 (96.0–108.0)104.0 (98.0–114.0)<  0.001
Fasting insulin (mU/L)9.0 (7.0–11.0)10.0 (8.0–12.0)12.0 (9.0–15.0)15.0 (11.0–20.0)16.0 (12.0–22.5)<  0.001
HOMA-IR2.1 (1.6–2.7)2.5 (1.9–2.9)2.8 (2.2–3.9)3.6 (2.7–5.2)4.1 (3.2–6.5)<  0.001
Center     0.3
 Minnesota106 (54)95 (48)85 (44)105 (53)90 (49) 
 Utah92 (46)105 (52)109 (56)94 (47)94 (51) 
Diabetes     <  0.001
 Yes6 (3)10 (5)9 (5)23 (12)26 (14) 
 No192 (97)190 (95)184 (95)176 (88)158 (86) 
Metabolic Syndrome     0.054
 Yes76 (38)82 (41)64 (33)55 (28)63 (34) 
 No122 (62)118 (59)130 (67)144 (72)121 (66) 
  1. * Median (IQRs) or n (%)
  2. Abbreviations: HOMA-IR Homeostatic model assessment-insulin resistance