Fig. 3
IκBα reduced cell injury in NRVMs exposed to H2O2. a Representative images of JC-1 staining in different groups (scale bar: 250 μm). The results indicated that IκBα or PDTC elevated the ratio of red to green fluorescence intensity (n = 3, * P < 0.05 and ** P < 0.01 vs. Control, #P < 0.05 vs. H2O2 group). b CCK-8 results demonstrated that IκBα or PDTC increased the cell viability of NRVMs stimulated by H2O2 (n = 3, * P < 0.05 and ** P < 0.01 vs. Control, #P < 0.05 vs. H2O2 group). c IκBα or PDTC reduced the levels of supernatant LDH in NRVMs subjected to H2O2 (n = 3, * P < 0.05 and ** P < 0.01 vs. Control, #P < 0.05 and ##P < 0.01 vs. H2O2 group). d IκBα or PDTC decreased the content of intracellular MDA in H2O2-treated NRVMs (n = 3, ** P < 0.01 vs. Control, #P < 0.05 vs. H2O2 group)