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Table 5 MDR analysis of SNP-SNP interactions

From: Contribution of CYP24A1 variants in coronary heart disease among the Chinese population

Model

Training Bal. Acc.

Testing Bal. Acc.

CV Consistency

Accuracy

Sensitivity

Specificity

OR(95%CI)

P

rs2296241

0.533

0.533

10/10

0.533

0.614

0.452

1.31 (1.02–1.68)

0.035

rs1570669,rs2296241

0.550

0.548

10/10

0.550

0.721

0.378

1.57 (1.20–2.05)

0.001

rs1570669,rs6068816,rs2296241

0.567

0.509

6/10

0.565

0.457

0.673

1.74 (1.35–2.24)

< 0.001

rs2762934,rs1570669,rs6068816,rs2296241

0.586

0.484

10/10

0.580

0.659

0.501

1.94 (1.51–2.50)

< 0.001

  1. MDR multifactor dimensionality reduction, SNP single nucleotide polymorphism, CV cross-validation, OR odds ratio, CI confidence interval
  2. Bold-faced values indicate significant difference (P < 0.05)
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Lipids in Health and Disease

ISSN: 1476-511X