Table 3 Stratified analysis of the association of CYP1A2 polymorphism with stroke risk
From: The influence of CYP1A1 and CYP1A2 polymorphisms on stroke risk in the Chinese population
SNP | Model | Genotype | >64ys | ≤64ys | Males | Females | ||||
|---|---|---|---|---|---|---|---|---|---|---|
OR(95% CI) | P-values | OR(95% CI) | P-values | OR(95% CI) | P-values | OR(95% CI) | P-values | |||
rs762551 | codominant | C/C | 1 | 1 | 1 | 1 | ||||
A/C | 0.75 (0.48–1.18) | 0.216 | 1.33 (0.89–2.00) | 0.166 | 1.04 (0.74–1.48) | 0.815 | 0.90 (0.56–1.45) | 0.666 | ||
A/A | 0.62 (0.33–1.18) | 0.148 | 0.66 (0.38–1.16) | 0.145 | 0.56 (0.34–0.90) | 0.017* | 0.68 (0.34–1.35) | 0.267 | ||
dominant | C/C | 1 | 1 | 1 | 1 | |||||
A/C-A/A | 0.72 (0.47–1.11) | 0.137 | 1.12 (0.76–1.65) | 0.562 | 0.89 (0.64–1.24) | 0.503 | 0.85 (0.54–1.34) | 0.472 | ||
recessive | C/C-A/C | 1 | 1 | 1 | 1 | |||||
A/A | 0.74 (0.41–1.32) | 0.302 | 0.56 (0.33–0.92) | 0.024* | 0.74 (0.41–1.32) | 0.302 | 0.72 (0.39–1.35) | 0.306 | ||
log-additive | – | 0.78 (0.58–1.06) | 0.111 | 0.89 (0.69–1.16) | 0.407 | 0.80 (0.64–1.00) | 0.053 | 0.84 (0.61–1.16) | 0.296 | |