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Fig. 6 | Lipids in Health and Disease

Fig. 6

From: Combined extracts of Moringa oleifera, Murraya koeingii leaves, and Curcuma longa rhizome increases energy expenditure and controls obesity in high-fat diet-fed rats

Fig. 6

Possible mechanisms of action of LI85008F. The herbal extract combination, LI85008F, down-regulates adipogenesis, and, in parallel, activates energy metabolism in white fat tissue (WAT) of the obese rats. PPARγ-dependent transcription factors include C/EBPα, CCAAT enhancer-binding protein alpha; aP-2α, Activating Protein 2α; CD36, cluster of differentiation 36 and perilipin. PPARγ, Peroxisome proliferator-activated receptor gamma; UCP-1, Uncoupling protein-1. The down headed arrows in red color indicate suppression or reductions; the up arrows in green color indicate up-regulation or increase of metabolic function. The symbol (?) indicates a suggested WAT browning, warrants further exploration

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Lipids in Health and Disease

ISSN: 1476-511X