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Fig. 5 | Lipids in Health and Disease

Fig. 5

From: Hyperhomocysteinemia and dyslipidemia in point mutation G307S of cystathionine β-synthase-deficient rabbit generated using CRISPR/Cas9

Fig. 5

CBS-KO rabbits showed signs of fatty liver. a Representative images of the liver from CBS-KO (C8) and WT rabbits. b Representative images of HE-stained liver sections from the indicated groups. CBS-KO-NC: CBS-KO rabbits (C8♀) fed normal chow. WT-NC: wild type rabbits fed normal chow. CBS-KO-SB: CBS-KO rabbits (C9♀) fed normal chow supplemented with vitamin B and betaine complex. WT-SB: wild type rabbits fed normal chow diet supplemented with vitamin B and betaine complex. Magnification – 200x; Scale bar = 50 μm. c Gross lesions of aortic atherosclerosis in CBS-KO rabbit (C8♀, 6 weeks) stained with Sudan IV

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