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Table 4 Subgroup analysis of triglycerides levels with mortality

From: A dose-independent association of triglyceride levels with all-cause mortality among adults population

 

Number

All-cause mortality

HR (95% CI) P-value

P for log likelihood ratio test

Cardiovascular disease mortality

HR (95% CI) P-value

P for log likelihood ratio test

Cutoff value, mmol/L

 

< 1.52

≥ 1.52

 

< 1.10

≥ 1.10

 

Age, years

  ≥ 65

2502

0.78 (0.60, 1.01) 0.0558

1.09 (0.99, 1.19) 0.0654

0.024

0.54 (0.19, 1.51) 0.2400

1.00 (0.84, 1.19) 0.9968

0.267

  < 65

9135

1.21 (0.87, 1.68) 0.2640

1.05 (0.95, 1.15) 0.3327

0.436

1.49 (0.30, 7.35) 0.6273

1.15 (0.96, 1.38) 0.1206

0.757

Gender

 Male

5659

0.91 (0.69, 1.19) 0.4874

1.14 (1.05, 1.23) 0.0016

0.136

0.85 (0.29, 2.50) 0.7651

1.21 (1.05, 1.40) 0.0096

0.527

 Female

5978

0.89 (0.65, 1.22) 0.4596

1.08 (0.97, 1.20) 0.1491

0.277

0.44 (0.10, 2.00) 0.2873

0.92 (0.72, 1.18) 0.5239

0.367

Body mass index, kg/m2

  ≥ 25

8102

0.90 (0.70, 1.16) 0.4312

1.11 (1.03, 1.19) 0.0036

0.143

0.70 (0.22, 2.19) 0.5437

1.09 (0.94, 1.26) 0.2783

0.471

  < 25

3535

0.78 (0.54, 1.12) 0.1821

1.23 (1.03, 1.47) 0.0244

0.050

0.43 (0.11, 1.67) 0.2241

1.44 (1.09, 1.90) 0.0095

0.105

Race

 Non-white

6114

1.00 (0.74, 1.35) 0.9952

1.05 (0.96, 1.16) 0.2861

0.757

0.34 (0.10, 1.11) 0.0738

1.17 (0.98, 1.39) 0.0916

0.054

 White

5523

0.79 (0.60, 1.05) 0.1088

1.16 (1.07, 1.27) 0.0007

0.016

1.08 (0.30, 3.96) 0.9055

1.07 (0.89, 1.27) 0.4852

0.982

Lipid-lowering drugs

 No

10,251

0.91 (0.73, 1.15) 0.4476

1.12 (1.05, 1.20) 0.0015

0.114

0.53 (0.20, 1.42) 0.2078

1.14 (0.98, 1.32) 0.0813

0.147

 Yes

1386

0.75 (0.48, 1.17) 0.2035

1.11 (0.96, 1.29) 0.1696

0.126

1.05 (0.16, 6.85) 0.9565

1.07 (0.83, 1.37) 0.6183

0.990

Hypertension

 No

6779

0.87 (0.59, 1.29) 0.4962

1.07 (0.94, 1.23) 0.2792

0.350

2.16 (0.22, 21.49) 0.5106

0.95 (0.68, 1.34) 0.7752

0.483

 Yes

4858

0.81 (0.64, 1.03) 0.0903

1.14 (1.06, 1.22) 0.0006

0.013

0.46 (0.18, 1.17) 0.1035

1.16 (1.01, 1.33) 0.0358

0.066

Diabetes

 No

9867

0.90 (0.71, 1.14) 0.3882

1.14 (1.04, 1.25) 0.0065

0.101

0.85 (0.30, 2.43) 0.7648

0.91 (0.72, 1.14) 0.4063

0.911

 Yes

1770

0.82 (0.55, 1.22) 0.3276

1.11 (1.01, 1.22) 0.0287

0.162

0.43 (0.09, 2.17) 0.3091

1.25 (1.07, 1.46) 0.0054

0.223

CVD

 No

10,646

0.93 (0.74, 1.18) 0.5569

1.10 (1.02, 1.18) 0.0142

0.217

0.83 (0.28, 2.43) 0.7333

1.01 (0.85, 1.20) 0.8977

0.727

 Yes

991

0.64 (0.42, 0.98) 0.0405

1.18 (1.04, 1.34) 0.0112

0.012

0.35 (0.07, 1.64) 0.1826

1.26 (1.04, 1.52) 0.0192

0.123

  1. Notes: Multivariate Cox regression was performed to examine the association between triglyceride levels and mortality
  2. Data are shown in HRs and 95%CI
  3. HR hazard ratios; CI confidence intervals; CAD coronary heart disease
  4. When analyzing a subgroup variable, age, gender, race, education level, smoking, body mass index, systolic blood pressure, estimated glomerular filtration rate, C-reactive protein, energy, total cholesterol, high density lipoprotein cholesterol, hypertension, diabetes, medicine use (antihypertensive drugs, hypoglycemic agents, lipid-lowering drugs, and antiplatelet drugs) were all adjusted except the variable itself
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Lipids in Health and Disease

ISSN: 1476-511X