Table 1 Clinical and biochemical characteristics

Number

1095

720 (65.75%)

375 (34.25%)

–

Age (years)

10.9 (8.4–13.1)

11.8 (8.4–13.5)

9.8 (8.2–11.6)

< 0.001

Height (cm)

134.20 (119.70–144.40)

137.20 (118.97–147.43)

131.50 (120.85–139.80)

< 0.001

Height SDS

−2.57 (−3.13--2.25)

− 2.59 (− 3.18--2.26)

−2.52 (− 3.07--2.23)

0.205

Body weight (kg)

30.00 (22.00–39.00)

31.00 (22.00–41.00)

29.00 (22.00–35.00)

< 0.001

BMI (kg/m²)

16.67 (15.16–19.01)

16.66 (15.18–19.37)

16.67 (15.13–18.56)

0.275

BMI SDS

− 0.17 (− 0.92–0.75)

− 0.21 (− 0.92–0.71)

−0.08 (− 0.95–0.80)

0.512

IGF-1 (ng/mL)

198.00 (114.75–321.00)

186.50 (108.00–295.75)

220.00 (138.50–359.00)

< 0.001

IGF-1 SDS

− 1.02 (− 1.84--0.18)

−1.00 (− 1.84--0.15)

−1.10 (− 1.84--0.20)

0.803

TG (mmol/L)

0.69 (0.53–0.91)

0.68 (0.53–0.90)

0.70 (0.54–0.94)

0.201

TC (mmol/L)

3.78 (3.37–4.25)

3.77 (3.37–4.24)

3.79 (3.38–4.26)

0.703

HDL-C (mmol/L)

1.33 (1.18–1.54)

1.34 (1.18–1.54)

1.33 (1.18–1.54)

0.727

LDL-C (mmol/L)

2.03 (1.70–2.39)

2.00 (1.70–2.36)

2.08 (1.74–2.40)

0.230

SUA (mg/dL)

4.52 (3.78–5.50)

4.60 (3.80–5.65)

4.40 (3.75–5.26)

0.010

Cr (μmol/L)

40.10 (34.02–46.40)

41.40 (34.82–48.50)

37.80 (32.60–43.12)

< 0.001

BUN (mmol/L)

4.40 (3.70–5.30)

4.70 (3.90–5.50)

4.10 (3.50–4.70)

< 0.001

Pubertal stage

< 0.001

In prepuberty (%)

624 (56.99%)

451 (62.64%)

173 (46.13%)

In puberty (%)

471 (43.01%)

269 (37.36%)

202 (53.87%)