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Table 3 Basic characteristics of the study population categorized by TBA quintiles

From: The association of serum total bile acid with non-alcoholic fatty liver disease in Chinese adults: a cross sectional study

 

Serum TBA quintiles

P

Q1 (n = 31,267)

Q2 (n = 30,136)

Q3 (n = 31,298)

Q4 (n = 29,245)

Q5 (n = 30,390)

Clinical characteristics

 Age, years

44 (12)

45 (13)

45 (13)

46 (14)

48 (15)

<.001

 Male percentage, % (n)

42.5% (13,284)

52.0% (15,679)

55.7% (17,428)

58.6% (17,129)

62.6% (19,013)

<.001

 BMI, kg/m2

23.7 (3.3)

24.0 (3.3)

24.1 (3.4)

24.2 (3.4)

24.3 (3.4)

<.001

 Systolic pressure, mm Hg

117 (17)

119 (17)

120 (17)

121 (17)

123 (18)

<.001

 Diastolic pressure, mm Hg

74 (11)

75 (11)

76 (11)

76 (11)

77 (11)

<.001

 NALFD, % (n)

20.8% (6512)

26.0% (7840)

28.8% (9012)

30.4% (8895)

31.3% (9512)

<.001

 Hypertension, % (n)

14.7% (4581)

17.6% (5309)

19.3% (6028)

21.9% (6403)

24.5% (7446)

<.001

 T2D, % (n)

2.0% (630)

3.1% (931)

3.7% (1161)

4.6% (1358)

5.1% (1543)

<.001

 CAD, % (n)

0.9% (269)

0.9% (282)

1.2% (387)

1.4% (407)

1.9% (575)

<.001

Biochemical parameters

     

<.001

 AST, U/L

20 (7)

21 (9)

22 (9)

23 (10)

26 (32)

<.001

 ALT, U/L

22 (14)

25 (18)

26 (20)

27 (22)

32 (44)

<.001

 BUN, mmol/L

4.8 (1.4)

4.9 (1.4)

5.1 (1.5)

5.1 (1.5)

5.1 (1.5)

<.001

 Cr, μmol/L

64.6 (21.7)

66.7 (21.5)

67.9 (26.6)

68.3 (21.7)

69.2 (20.5)

<.001

 UA, μmol/L

299.1 (80.3)

310.4 (82.6)

314.7 (83.2)

317.3 (83.8)

320.6 (84.2)

<.001

 FBG, mmol/L

4.90 (1.01)

4.98 (1.18)

5.04 (1.31)

5.11 (1.41)

5.16 (1.49)

<.001

 TC, mmol/L

4.65 (0.91)

4.66 (0.92)

4.66 (0.92)

4.67 (0.95)

4.66 (0.97)

0.103

 HDLC, mmol/L

1.35 (0.29)

1.32 (0.29)

1.30 (0.29)

1.29 (0.30)

1.28 (0.31)

<.001

 LDLC, mmol/L

2.70 (0.76)

2.69 (0.77)

2.68 (0.77)

2.67 (0.78)

2.62 (0.78)

<.001

 RLP-C, mmol/L

0.60 (0.47)

0.65 (0.56)

0.68 (0.60)

0.71 (0.66)

0.76 (0.74)

<.001

 TG, mmol/L

1.11 (0.80–1.61)

1.21 (0.84–1.81)

1.25 (0.87–1.90)

1.30 (0.89–1.97)

1.34 (0.92–2.06)

<.001

  1. Data are shown as mean (standard deviation), median (Q1–Q3 quartiles), or percentages (n). P values from analysis of the ANOVA, Kruskal-Wallis H test, or chi-square test. Two-tailed p < 0.05 was considered statistically significant. BMI body mass index, NALFD non-alcoholic fatty liver disease, T2D type 2 diabetes, CAD coronary artery disease, TBA total bile acid, FBG fasting blood glucose, AST aspartate aminotransferase, ALT alanine aminotransferase, BUN blood urea nitrogen, Cr creatinine, UA uric acid, TC total cholesterol, LDL-C LDL cholesterol, HDL-C HDL cholesterol, RLP-C remnant lipoprotein cholesterol, TG triglyceride
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Lipids in Health and Disease

ISSN: 1476-511X