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Table 4 The explained variance in TG levels using a polygenic risk score in FHTG and CHTG

From: Familial hypertriglyceridemia: an entity with distinguishable features from other causes of hypertriglyceridemia

Group

Explained variance (%)

[IC 0.025–0.975]

P

FHTG

1.78 [0.45–4.47]

< 2.2 × 10−16

CHTG

6.73 [0.47–9.56]

  1. IC from bootstrapped R-squared of models performing linear regression of TG levels on polygenic scores. The polygenic risk score was computed using the complete set of 38 known TG associated variants. P value of the comparison between the variance explained in FHTG versus CHTG
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Lipids in Health and Disease

ISSN: 1476-511X