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Table 1 Characteristics of observational studies in this systematic review and meta-analysis

From: A meta-analysis of HDL cholesterol efflux capacity and concentration in patients with rheumatoid arthritis

Authors Country Age
(mean)
Study type Subjects
(female, %)
Durationa
(month)
Assay method of CEC Labeled-cholesterol Quality
score
Outcome summary BMI
Ronda et al., 2013 [17] USA 45.0 Case-control 52 (86.7) NAc J774, Fu5AH, CHO-k1 to ApoB-depleted serum 3H-cholesterol 5 CECb is impaired in RA NA
Vivekanandan-Giri et al., 2013 [18] USA 56.6 Case-control 34 (58.6) 4.0 J774 to ApoB-depleted serum 3H-cholesterol 5 CEC was diminished in RA patients Case: 27 ± 5 Control: 27 ± 7
Charles-Schoeman et al., 2015 [19] USA 54.0 Case-control 66 (82.0) 12.8 RAW264.7 to isolated HDL 3H-cholesterol 9 no difference of CEC between RA patients and controls Case: 28 ± 7
Control: 25 ± 4
O’Neill et al., 2016 [20] UK 59.1 Case-control 22 (73.0) 5.0 J774 to ApoB-depleted serum 3H-cholesterol 7 Case: 24 ± 4
Control: 26 ± 2
Ormseth et al.,2016 [21] USA 54.0 Cross-sectional 144 (68.6) 3.9 THP-1 to ApoB-depleted serum 3H-cholesterol 6 CEC is not significantly altered in RA patients Case: 28 (24, 33)
Control: 27 (25, 32)
Tejera-Segura et al., 2017 [22] Spain 57.2 Cross-sectional 295 (73.6) 7.0 J774 to ApoB-depleted serum BODIPY-cholesterol 7 CEC is not significantly altered in RA patients Case: 28 ± 5
Control: 28 ± 5
  1. Data are presented as median (interquartile range) or mean ± SD unless otherwise indicated; a duration of RA; b cholesterol efflux capacity; c not available