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Table 4 Stratified associations between LDL/HDL cholesterol ratio and NAFLD by gender, age, and FPG

From: LDL/HDL cholesterol ratio is associated with new-onset NAFLD in Chinese non-obese people with normal lipids: a 5-year longitudinal cohort study

  

LDL/HDL cholesterol ratio (Quintile), HR (95%CI)

 

No. of cases

Q1

Q2

Q3

Q4

Q5

P-interaction

Gender

      

> 0.05

 Female

393 (46.73%)

Ref

1.84 (1.13, 3.01)

2.17 (1.36, 3.47)

2.17 (1.36, 3.45)

2.58 (1.64, 4.05)

 

 Male

448 (53.27%)

1.08 (0.64, 1.85)

1.73 (1.07, 2.82)

1.72 (1.07, 2.77)

1.84 (1.16, 2.91)

2.48 (1.59, 3.88)

 

Age, years

      

< 0.05

  ≥ 60

127 (15.10%)

Ref

3.31 (1.66, 6.62)

1.57 (0.73, 3.39)

1.42 (0.67, 3.01)

2.23 (1.14, 3.34)

 

  ≥ 45, < 60

247 (29.37%)

1.74 (0.78, 3.87)

2.05 (0.93, 4.48)

2.26 (1.07, 4.75)

2.46 (1.17, 5.16)

3.50 (1.70, 7.20)

 

  ≥ 30, < 45

325 (38.64%)

1.06 (0.41, 2.72)

2.26 (0.94, 5.42)

3.01 (1.27, 7.08)

3.10 (1.33, 7.20)

3.30 (1.43, 7.59)

 

  < 30

142 (16.88%)

1.78 (0.57, 5.56)

1.67 (0.58, 4.80)

2.66 (0.94, 7.54)

2.81 (1.04, 7.56)

3.96 (1.50, 10.46)

 

FPG, mmol/l

      

> 0.05

  ≤ 6.1

745 (88.59%)

Ref

1.70 (1.20, 2.41)

1.97 (1.40, 2.76)

1.93 (1.38, 2.70)

2.50 (1.80, 3.47)

 

  > 6.1

96 (11.41%)

2.08 (1.04, 4.19)

4.16 (2.20, 7.89)

3.24 (1.86, 5.64)

3.74 (2.18, 6.39)

3.96 (2.48, 6.32)

 
  1. Adjusted for TC, TG and BMI; Model III adjusted for gender, age, ALP, GGT, ALT, AST, ALB, GLB, DBIL, CR, UA, FPG, TC, TG, height, BMI, SBP and DBP
  2. Note: the model was not adjusted for the stratification variable
  3. Abbreviations: CI confidence interval, HR hazard ratios, FPG fasting plasma glucose, NAFLD nonalcoholic fatty liver disease