Risk stratification of ST-segment elevation myocardial infarction (STEMI) patients using machine learning based on lipid profiles

Table 3 Multivariable cox analysis of association between lipid-derived phenogroups and outcomes during follow-up

	Phenogroup 1 (n = 415)		Phenogroup 2 (n = 496)			Phenogroup 3 (n = 444)
Outcomes	Events	Reference	Events	HR (95% CI)	P-value	Events	HR (95% CI)	P-value
All-cause mortality	64 (15.4%)	Ref.	67 (13.7%)	0.62 (0.37–0.99)	0.04	35 (7.9%)	0.54 (0.28–0.96)	0.001
All-cause rehospitalization	149 (35.9%)	Ref.	160 (32.3%)	0.80 (0.61–0.98)	0.03	113 (25.5%)	0.76 (0.57–0.97)	0.01
Cardiac rehospitalization	137 (33.0%)	Ref.	144 (29.0%)	0.75 (0.57–0.96)	0.02	97 (21.8%)	0.74 (0.54–0.97)	0.04

Outcomes were adjusted for age, gender, history of diabetes, hypertension, smoking status, culprit artery, creatinine, LVEF, hsCRP, cTNI, time to balloon (h), post procedural TIMI (≤2)
Abbreviations: LVEF left ventricular ejection fraction, hsCRP high sensitivity C-reactive protein, cTNI cardiac troponin I, TIMI thrombolysis in myocardial infarction

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