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Table 3 Univariate and multivariate Cox proportional hazards model analysis for overall survival

From: Prognostic significance of preoperative serum triglycerides and high-density lipoproteins cholesterol in patients with non-small cell lung cancer: a retrospective study

Characteristics Univariate analysis Multivariate analysis
HR 95%CI P value HR 95%CI P value
Age    0.023    0.013
  ≤ 57 1.000 Reference   1.000 Reference  
 >57 1.458 1.053–2.020   1.524 1.091–2.129  
Gender    0.139    
 Male 1.000 Reference     
 Female 0.777 0.556–1.086     
Smoking history    0.120    
 Y 1.000 Reference     
 N 0.775 0.563–1.068     
Stage    <0.001    0.051
 I-II 1.000 Reference   1.000 Reference  
 IIIA 3.075 2.279–4.148   1.747 0.997–3.060  
Pathological tumor       
Classification (pT)    0.009    0.285
 pT1–2 1.000 Reference   1.000 Reference  
 pT3–4 1.663 1.138–2.430   1.295 0.806–2.078  
Pathological lymph node       
stage (pN)    <0.001    <0.001
 pN0 1.000 Reference   1.000 Reference  
 pN1–2 3.842 2.772–5.323   4.574 2.694–7.767  
Histological type    0.136    
 Squamous cell carcinoma 1.000 Reference     
 Adenocarcinoma 0.847 0.611–1.173     
 Large cell carcinoma 1.371 0.815–2.305     
Surgery type    <0.001    0.613
 Lobectomy 1.000 Reference   1.000 Reference  
 Pneumonectomy 2.379 1.719–3.293   1.250 0.760–2.056  
 Other 2.231 1.316–3.781   1.026 0.543–1.938  
Adjuvant chemotherapy    <0.001    0.002
 Y 1.000 Reference   1.000 Reference  
 N 2.190 1.596–3.006   2.607 1.439–4.723  
GLU (mmol/L)    0.115    
  ≤ 5.75 1.000 Reference     
 >5.75 0.761 0.542–1.068     
TC (mmol/L)    0.490    
  ≤ 4.59 1.000 Reference     
 >4.59 0.896 0.655–1.225     
TG (mmol/L)    <0.001    <0.001
  ≤ 1.21 1.000 Reference   1.000 Reference  
 >1.21 2.217 1.640–2.997   1.891 1.385–2.583  
HDL-C (mmol/L)    <0.001    <0.001
  ≤ 1.26 1.000 Reference   1.000 Reference  
 >1.26 0.371 0.260–0.527   0.430 0.301–0.613  
LDL-C (mmol/L)    0.046    0.742
  ≤ 2.26 1.000 Reference   1.000 Reference  
 >2.26 1.399 1.006–1.945   1.059 0.752–1.492  
ApoA1(g/L)    0.181    
  ≤ 1.21 1.000 Reference     
 >1.21 0.811 0.597–1.102     
ApoB(g/L)    0.222    
  ≤ 1.15 1.000 Reference     
 >1.15 0.726 0.434–1.214     
Lpa (mg/L)    0.374    
  ≤ 53 1.000 Reference     
 >53 0.828 0.546–1.256     
  1. Data were analyzed by Cox proportional hazards model. P < 0.05 was considered significant
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Lipids in Health and Disease

ISSN: 1476-511X