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Table 3 Univariate and multivariate Cox proportional hazards model analysis for overall survival

From: Prognostic significance of preoperative serum triglycerides and high-density lipoproteins cholesterol in patients with non-small cell lung cancer: a retrospective study

Characteristics

Univariate analysis

Multivariate analysis

HR

95%CI

P value

HR

95%CI

P value

Age

  

0.023

  

0.013

  ≤ 57

1.000

Reference

 

1.000

Reference

 

 >57

1.458

1.053–2.020

 

1.524

1.091–2.129

 

Gender

  

0.139

   

 Male

1.000

Reference

    

 Female

0.777

0.556–1.086

    

Smoking history

  

0.120

   

 Y

1.000

Reference

    

 N

0.775

0.563–1.068

    

Stage

  

<0.001

  

0.051

 I-II

1.000

Reference

 

1.000

Reference

 

 IIIA

3.075

2.279–4.148

 

1.747

0.997–3.060

 

Pathological tumor

      

Classification (pT)

  

0.009

  

0.285

 pT1–2

1.000

Reference

 

1.000

Reference

 

 pT3–4

1.663

1.138–2.430

 

1.295

0.806–2.078

 

Pathological lymph node

      

stage (pN)

  

<0.001

  

<0.001

 pN0

1.000

Reference

 

1.000

Reference

 

 pN1–2

3.842

2.772–5.323

 

4.574

2.694–7.767

 

Histological type

  

0.136

   

 Squamous cell carcinoma

1.000

Reference

    

 Adenocarcinoma

0.847

0.611–1.173

    

 Large cell carcinoma

1.371

0.815–2.305

    

Surgery type

  

<0.001

  

0.613

 Lobectomy

1.000

Reference

 

1.000

Reference

 

 Pneumonectomy

2.379

1.719–3.293

 

1.250

0.760–2.056

 

 Other

2.231

1.316–3.781

 

1.026

0.543–1.938

 

Adjuvant chemotherapy

  

<0.001

  

0.002

 Y

1.000

Reference

 

1.000

Reference

 

 N

2.190

1.596–3.006

 

2.607

1.439–4.723

 

GLU (mmol/L)

  

0.115

   

  ≤ 5.75

1.000

Reference

    

 >5.75

0.761

0.542–1.068

    

TC (mmol/L)

  

0.490

   

  ≤ 4.59

1.000

Reference

    

 >4.59

0.896

0.655–1.225

    

TG (mmol/L)

  

<0.001

  

<0.001

  ≤ 1.21

1.000

Reference

 

1.000

Reference

 

 >1.21

2.217

1.640–2.997

 

1.891

1.385–2.583

 

HDL-C (mmol/L)

  

<0.001

  

<0.001

  ≤ 1.26

1.000

Reference

 

1.000

Reference

 

 >1.26

0.371

0.260–0.527

 

0.430

0.301–0.613

 

LDL-C (mmol/L)

  

0.046

  

0.742

  ≤ 2.26

1.000

Reference

 

1.000

Reference

 

 >2.26

1.399

1.006–1.945

 

1.059

0.752–1.492

 

ApoA1(g/L)

  

0.181

   

  ≤ 1.21

1.000

Reference

    

 >1.21

0.811

0.597–1.102

    

ApoB(g/L)

  

0.222

   

  ≤ 1.15

1.000

Reference

    

 >1.15

0.726

0.434–1.214

    

Lpa (mg/L)

  

0.374

   

  ≤ 53

1.000

Reference

    

 >53

0.828

0.546–1.256

    
  1. Data were analyzed by Cox proportional hazards model. P < 0.05 was considered significant