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Fig. 1 | Lipids in Health and Disease

Fig. 1

From: The effects of exercise training versus intensive insulin treatment on skeletal muscle fibre content in type 1 diabetes mellitus rodents

Fig. 1

Examples of serial sections with three histochemical stains used in fibre quantification, from left to right: a Metachromatic myosin ATPase (stain to identify muscle fibre type), b Glycogen Periodic Acid Schiff (stain to identify high/low glycogen content), and c Oil Red O (stain for high/low IMCL content). See Additional file 1 for quantification example. Note that Oil Red O-stained neutral lipids appear to primarily exist around the internal periphery of the cell membrane, suggesting a possible role for subcellular localization of lipid droplets in the utility of IMCL

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