Fig. 2

Complete blood glucose and body weight data are presented in (a) and (b), respectively. These data were collected for 17 male rats across four groups throughout the duration of the study. † denotes the start of streptozotocin injections to induce type 1 diabetes; ‡ denotes the start of insulin treatment; and ¶ denotes the start of exercise regimen. a Mean non-fasted weekly BG measures (mmol/L). All data presented as mean ± SEM. * denotes P ≤ 0.0001. Insulin was administered through subcutaneous implants, and pellet dosage was adjusted throughout the study to maintain desired blood glucose ranges b Mean weekly body mass measures (g). All data presented as mean ± SEM. * denotes P = 0.0059, ** denotes P < 0.0001. The four groups compared were Control Sedentary (CS); diabetic with conventional insulin therapy (DCT); diabetic with intensive insulin therapy (DIT); and diabetic with combined exercise training and conventional insulin therapy (DARE). Note that the body mass of all three diabetic groups was significantly lower than the mass of the CS group (P < 0.0001)