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Table 8 Associations between HDL-C and osteopenia or osteoporosis in females

From: High-density Lipoprotein Cholesterol Is Negatively Correlated with Bone Mineral Density and Has Potential Predictive Value for Bone Loss

 

Age (20-29)

Age (30-39)

Age (40-49)

Age (50-59)

Age (60-)

Total

Non-adjusted

 HDL (49-61 mg/dL)

Reference

Reference

Reference

Reference

Reference

Reference

 HDL (21-48 mg/dL)

0.9387 (0.5986, 1.4718) 0.782692

0.5797 (0.3550, 0.9466) 0.029321

1.9966 (1.2513, 3.1860) 0.003729

0.9575 (0.5839, 1.5700) 0.863251

0.8372 (0.5043, 1.3900) 0.492132

0.9872 (0.7972, 1.2224) 0.905687

 HDL (62-139 mg/dL)

1.0672 (0.6872, 1.6575) 0.772075

1.3464 (0.8806, 2.0587) 0.169779

2.5978 (1.6734, 4.0328) 0.000021

2.7259 (1.6882, 4.4014) 0.000041

1.5604 (0.9488, 2.5663) 0.079599

1.7096 (1.4004, 2.0869) <0.000001

Adjusted

 HDL (49-61 mg/dL)

Reference

Reference

Reference

Reference

Reference

Reference

 HDL (21-48 mg/dL)

1.2054 (0.7176, 2.0251) 0.480194

0.6875 (0.3996, 1.1829) 0.175989

2.4873 (1.4866, 4.1618) 0.000521

1.0997 (0.6186, 1.9549) 0.746046

1.1149 (0.5826, 2.1335) 0.742546

1.1529 (0.9135, 1.4550) 0.230883

 HDL (62-139 mg/dL)

0.9365 (0.5670, 1.5466) 0.797616

1.1742 (0.7322, 1.8830) 0.505203

2.0781 (1.2673, 3.4075) 0.003744

2.3301 (1.3215, 4.1085) 0.003463

1.5008 (0.7983, 2.8214) 0.207419

1.3831 (1.1118, 1.7207) 0.003602

  1. Race/ethnicity (Mexican American; other Hispanic; non-Hispanic white; non-Hispanic black; other races), education level (under high school; high school or equivalent; above high school), income to poverty ratio (quartile groups), BMI (obese, overweight, normal), smoking status (less than 100 cigarettes; greater than or equal to 100 cigarettes), alcohol consumption status (had at least 12 alcohol drinks past one year; have less than 12 alcohol drinks past one year), hypertension (yes; no), diabetes (yes; no; borderline), ALT (quartile groups), AST (quartile groups), total calcium (quartile groups), cholesterol (quartile groups), and C-reactive protein (quartile groups) were adjusted. HDL-C, high-density lipoprotein cholesterol; ALT alanine aminotransferase; AST aspartate aminotransferase