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Fig. 4 | Lipids in Health and Disease

Fig. 4

From: miR-410-3P inhibits adipocyte differentiation by targeting IRS-1 in cancer-associated cachexia patients

Fig. 4

IRS1 is a target of miR-410-3P. a. The matching of miR-410-3p with 3’-untranslated regions (UTR) of IRS-1. b and c. qPCR analyses and Western Blot analyses of IRS-1 in NC group and miR-410-3p mimics concentration gradient (200nM and 300nM) group. d and e. qPCR analyses and Western Blot analyses of IRS-1 in NC group and miR-410-3p inhibitors concentration gradient (200nM and 300nM) group. f. the different sequences of luciferase reporter plasmid weird type (WT) and mutated type (MT).g. Luciferase reporter assay in HEK293T cells. All data are expressed as mean ± SEM. * P < 0.05, ** P < 0.01, *** P < 0.001

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Lipids in Health and Disease

ISSN: 1476-511X