Lipids in Health and Disease

Table 3 Allelic distribution of previously known APOC3 rare variants and their association with TG, HDL-C, and CAD only in Asian Indians

From: APOC3 genetic variation, serum triglycerides, and risk of coronary artery disease in Asian Indians, Europeans, and other ethnic groups

Variant	Carrier	Non-Carrier	% Carriers	Mean TG (mg/dL) Carrier/Non-carrier	Mean HDL mg/dL Carrier/Non-carriers	CAD Among Carriers	CAD Among Non-carriers	Odds Ratio/CI/P (CAD)
rs373975305 (IVS1-2G-A)	12	23,871	0.05	166.6/173.6 (−4%)	44/42.6 (3.3%)	0/12	4364/19507	0.18 95%CI (0.01–3.02); p = 0.233
rs76353203 (R19X)	3	23,880	0.01	84.9/171.5 (−50.5%)	55.1/43.3 (27.3%)	0/3	4364/19516	0.64 95%CI (0.03–12.37); p = 0.767
rs138326449 (IVS2 + 1G-A)	4	23,879	0.02	101/165.8 (−39.1%)	46.7/46.2 (1.1%)	0/4	4351/19528	0.50 95%CI (0.03–9.26); p = 0.641
rs147210663 (A43T)	22	23,861	0.09	175.2/171.5 (2.2%)	42.7/43.4 (−1.6%)	0/22	4364/19497	0.09 95%CI (0.01–1.64); p = 0.106
rs140621530 (IVS3 + 1G-T)	12	23,871	0.05	221/173.6 (27.3%)	43/42.6 (0.9%)	0/12	4364/19507	0.18 95%CI (0.01–3.02); p = 0.233

Variant data from Singapore Asian Indians (MEC_ Indian and SINDI) were not included because of the lack of information on CAD

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