Subgroup | No. of participants | unadjusted HR (95Â %CI) | adjusted HR (95Â %CI) | P for interaction |
---|---|---|---|---|
Age (years) | Â | Â | Â | 0.0095 |
 20–30 | 14,934 | 2.81 (2.34, 3.36) | 1.83 (1.24, 2.70) |  |
 31–40 | 41,461 | 2.79 (2.58, 3.01) | 2.16 (1.90, 2.47) |  |
 41–50 | 26,038 | 2.58 (2.41, 2.76) | 1.87 (1.65, 2.12) |  |
 51–60 | 19,151 | 2.06 (1.95, 2.19) | 1.45 (1.31, 1.61) |  |
 61–70 | 10,701 | 1.67 (1.55, 1.80) | 1.14 (1.01, 1.29) |  |
 >70 | 4376 | 1.56 (1.40, 1.74) | 1.26 (1.08, 1.48) |  |
Sex | Â | Â | Â | 0.0651 |
 Male | 62,759 | 2.13 (2.05, 2.22) | 1.44 (1.33, 1.55) |  |
 Female | 53,902 | 2.51 (2.39, 2.64) | 1.59 (1.45, 1.74) |  |
BMI (kg/m2) |  |  |  | < 0.0001 |
 <24 | 69,459 | 5.57 (4.92, 6.31) | 2.32 (1.86, 2.89) |  |
 ≥24, < 28 | 37,086 | 3.47 (3.15, 3.82) | 1.68 (1.38, 2.04) |  |
 ≥ 28 | 10,116 | 1.80 (1.65, 1.97) | 1.25 (1.07, 1.45) |  |