Characteristics N = 3684 |  | HR (95% CI) | P-value |
---|---|---|---|
Gender (female = 1, male = 2) | 2 vs 1 | 1.43 (1.04–1.98) | 0.027 |
Age (per 1 year) | – | 1.09 (1.08–1.11) | <  0.001 |
Body mass index categories (<  18.5 kg/m2 = 1, 18.5–24.9 kg/m2 = 2, ≥ 25.0 kg/m2 = 3) | 2 vs 1 3 vs 1 | 0.51 (0.35–0.75) 0.40 (0.26–0.63) | 0.001 <  0.001 |
Smoking habits (non = 1, ex = 2, light = 3, heavy = 4) | 2 vs 1 3 vs 1 4 vs 1 | 1.29 (0.97–1.72) 0.34 (0.11–1.07) 0.97 (0.50–1.90) | 0.085 0.064 0.934 |
Drinking habits (non = 1, occasional = 2, light = 3, heavy = 4) | 2 vs 1 3 vs 1 4 vs 1 | 1.02 (0.76–1.38) 0.85 (0.59–1.23) 0.95 (0.61–1.49) | 0.880 0.394 0.834 |
History of cardiovascular disease (no = 1, yes = 2) | 2 vs 1 | 1.33 (0.99–1.80) | 0.061 |
Hypertension (no = 1, yes = 2) | 2 vs 1 | 1.09 (0.84–1.40) | 0.528 |
Hypertriglyceridemia (no = 1, yes = 2) | 2 vs 1 | 0.92 (0.67–1.26) | 0.604 |
Low HDL-cholesterolemia (no = 1, yes = 2) | 2 vs 1 | 0.54 (0.29–1.00) | 0.052 |
LDL cholesterol categories (<  70 mg/dL = 1, 70–92 mg/dL = 2, 93–143 mg/dL = 3, ≥ 144 mg/dL = 4) | 1 vs 4 2 vs 4 3 vs 4 | 2.54 (1.58–4.07) 1.71 (1.15–2.54) 1.21 (0.87–1.68) | <  0.001 0.008 0.250 |
Lipid-lowering medication (no = 1, yes = 2) | 2 vs 1 | 0.89 (0.60–1.31) | 0.551 |
Diabetes (no = 1, yes = 2) | 2 vs 1 | 1.66 (1.23–2.23) | 0.001 |
Chronic kidney disease (no = 1, yes = 2) | 2 vs 1 | 0.93 (0.69–1.27) | 0.659 |
Hyperuricemia (no = 1, yes = 2) | 2 vs 1 | 1.17 (0.85–1.60) | 0.337 |