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Table 1 Baseline MHD patient characteristics according to Non-HDL-C quartile

From: Non-high-density lipoprotein cholesterol may predict the cardio-cerebrovascular risk in patients on maintenance hemodialysis

Characteristic

Non-HDL-C Quartile

p-value

Q1 < 2.24

2.24 ≤ Q2<2.76

2.76 ≤ Q3<3.45

Q4 ≥ 3.45

n = 314

n = 323

n = 326

n = 325

Age (years)

57.89 ± 14.17

59.84 ± 15.09

59.47 ± 15.51

62.86 ± 15.07

< 0.001

Gender

    

0.469

 male, n (%)

185(58.9%)

194(60.1%)

184(56.4%)

203(62.5%)

 

 female, n (%)

129(41.1%)

129(39.9%)

142(43.6%)

122(37.5%)

 

Dialysis time (months)

28.11(14.09–65.67)

25.17(11.56–53.33)

23.90(9.50–50.40)

26.47(7.99–47.01)

 

BMI (kg/m2)

19.71(14.50–25.00)

19.71(0.00–23.55)

19.59(0.00–24.72)

22.52(16.51–27.77)

< 0.001

Cause of ESRD, n (%)

    

< 0.001

 primary glomerulonephritis

177(56.4%)

161(50.0%)

164(50.5%)

120(36.9%)

 

 diabetic nephropathy

65(20.7%)

68(21.1%)

68(20.9%)

87(26.8%)

 

 hypertensive nephropathy

19(6.1%)

12(3.7%)

12(3.7%)

18(5.5%)

 

Anticoagulant type, n (%)

    

0.136

 low molecular weight heparin

282(89.8%)

274(84.8%)

276(84.9%)

271(83.4%)

 

 unfractionated heparin

30(9.6%)

42(13.0%)

41(12.6%)

42(12.9%)

 

Dialysis vascular access, n (%)

    

0.033

 AVF

268(85.4%)

277(85.8%)

278(85.3%)

262(80.6%)

 

 AVG

3(1.0%)

2(0.6%)

6(1.8%)

6(1.8%)

 

 TCC

30(9.6%)

37(11.5%)

24(7.4%)

31(9.5%)

 

 NCC

13(4.1%)

7(2.2%)

18(5.5%)

26(8.0%)

 

Mean UFV(L)

2.43(1.93–3.00)

2.40(1.65–2.93)

2.23(1.66–2.84)

2.30(1.71–3.16)

0.788

Systolic pressure (mmHg)

146.35 ± 18.99

145.72 ± 21.37

146.71 ± 20.86

145.37 ± 20.77

0.838

Diastolic pressure (mmHg)

82.84 ± 11.89

82.50 ± 12.49

84.68 ± 50.09

84.17 ± 40.21

0.814

Diabetes, n (%)

59(18.8%)

63(19.5%)

77(23.7%)

71(21.8%)

0.404

FPG (mmol/L)

4.35 ± 1.81

6.99 ± 3.02

4.86 ± 1.25

7.42 ± 2.84

0.058

Tc (mmol/L)

4.40 ± 1.28

3.87 ± 0.42

5.20 ± 1.25

5.32 ± 0.24

< 0.001

Tg (mmol/L)

3.36 ± 2.85

0.81 ± 0.25

1.67 ± 1.55

3.09 ± 2.75

< 0.001

LDL-C (mmol/L)

2.88(2.40–3.70)

2.06(1.83–2.33)

1.69(1.39–2.66)

2.02(1.54–2.41)

< 0.001

HDL-C (mmol/L)

1.14(0.92–1.44)

1.08(0.88–1.27)

1.07(0.88–1.34)

1.07(0.85–1.42)

0.052

Alb (g/L)

22.04 ± 17.71

42.75 ± 1.89

31.74 ± 16.65

37.75 ± 3.09

< 0.001

Cr (μmol/L)

554.36 ± 563.53

1082.75 ± 161.16

937.10 ± 654.46

1194.25 ± 307.89

< 0.001

BUN (μmol/L)

27.18(22.64–34.00)

27.40(22.80–33.90)

26.18(22.18–32.43)

26.97(22.00–34.12)

0.638

Ua (μmol/L)

266.60 ± 211.82

458.75 ± 35.85

465.30 ± 271.41

547.25 ± 133.98

< 0.001

Total Kt/V

1.33(1.12–1.60)

1.32(1.18–1.50)

1.32(1.18–1.48)

1.37(1.12–1.76)

0.029

WBC (109/L)

4.72 ± 1.44

6.40 ± 1.45

6.15 ± 2.53

7.00 ± 1.31

0.035

Hb (g/L)

128.27 ± 34.91

99.00 ± 12.02

107.00 ± 41.59

90.25 ± 26.53

< 0.001

Plt (109/L)

131.90 ± 51.11

23.17 ± 2.92

30.83 ± 22.22

24.84 ± 4.37

< 0.001

K (mmol/L)

5.31(4.62–6.40)

5.15(4.50–5.70)

5.05(4.60–5.62)

5.40(4.63–7.00)

0.084

Ca (mmol/L)

2.20(2.08–2.36)

2.16(2.00–2.32)

2.15(2.04–2.31)

2.31(2.12–2.76)

0.012

PTH (pg/ml)

167.60(38.65–403.60)

260.96(75.05–585.33)

234.41(72.90–624.25)

233.93(79.03–587.40)

0.009

P (mmol/L)

6.80 ± 5.89

1.79 ± 0.47

3.56 ± 2.83

2.46 ± 0.44

< 0.001

  1. Values are expressed as mean ± SD, median and interquartile range, or number (percentage) as appropriate. BMI Body mass index, ESRD End-stage renal disease, AVF Autogenous arteriovenous fistula, AVG Arteriovenous graft, TCC Tunnel-cuffed catheter, NCC Non-cuffed catheter, UFV Ultrafiltration volume, CVD Cardiovascular disease, FPG Fasting plasma glucose, Tc Total cholesterol, Tg Triglycerides, LDL-c Low density lipoprotein cholesterol, HDL-C High-density lipoprotein cholesterol, Alb Albumin, Cr Creatinine, BUN Blood urea nitrogen, Ua Uric acid, Hb Hemoglobin, Plt Platelets, Pth Parathyroid hormone