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Table 4 Lipid levels and the results of two-way ANOVA with AF groups and the three APOE alleles

From: Association between the APOE gene polymorphism and lipid profile and the risk of atrial fibrillation

 

APOE allele groups

AF groups

ANOVA interaction

(AF and APOE alleles)

ε2(n = 203)

ε3(n = 758)

ε4(n = 379)

AF (n = 693)

Non-AF (n = 647)

F

P

TC (mmol/L)

3.737(0.075;3.590–3.884)

4.253(0.039;4.177–4.329)

4.512(0.055;4.404–4.621)

4.404(0.047;4.312–4.496)

3.930(0.048;3.386–4.025)

6.189

0.002

TG

(mmol/L)

1.045(0.050;0.947–1.143)

1.264(0.026;1.214–1.315)

1.490(0.037;1.417–1.562)

1.380(0.031;1.319–1.441)

1.153(0.032;1.090–1.216)

4.478

0.012

HDL-C

(mmol/L)

1.275(0.027;1.223–1.327)

1.240(0.014;1.213–1.267)

1.188(0.020;1.149–1.226)

1.248(0.017;1.215–1.280)

1.221(0.017;1.187–1.254)

0.214

0.808

LDL-C

(mmol/L)

1.857(0.053;1.753–1.962)

2.340(0.028;2.286–2.394)

2.566(0.039;2.488–2.643)

2.406(0.033;2.340–2.471)

2.103(0.034;2.035–2.170)

3.717

0.025

Apo-A1

(g/L)

1.066(0.023;1.020–1.111)

1.074(0.012;1.050–1.097)

1.066(0.017;1.033–1.099)

1.049(0.014;1.021–1.077)

1.088(0.015;1.059–1.117)

0.264

0.768

Apo-B

(g/L)

0.620(0.017;0.587–0.654)

0.763(0.009;0.745–0.780)

0.833(0.013;0.808–0.857)

0.785(0.011;0.764–0.806)

0.692(0.011;0.670–0.713)

4.529

0.011

  1. Mean (SD; range)
  2. AF: atrial fibrillation
  3. TC: total cholesterol
  4. TG: triglyceride
  5. HDL-C: high-density lipoprotein cholesterol
  6. LDL-C: low-density lipoprotein cholesterol
  7. Apo-A1: apolipoprotein A1
  8. Apo-B: apolipoprotein B