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Table 1 Baseline characteristics of enrolled population

From: Association between the triglyceride glucose index and coronary collateralization in coronary artery disease patients with chronic total occlusion lesions

  Total populations Rentrop Classification (0-1) Rentrop Classification
(2-3)
P
(n=1093) (n=318) (n=775)
Demographic data     
Age (years) 58.76±10.17 58.0±10.11 59.1±10.19 0.064
Male sex, n (%) 936 (85.6 %) 270 (85 %) 666 (86 %) 0.659
BMI (Kg/m²) 26.4±3.30 26.7±3.21 26.2±3.32 0.019*
SBP (mmHg) 130.1±16.49 129.7±15.63 130.3±16.84 0.721
DBP (mmHg) 77.1±11.22 77.3±10.54 77.0±11.49 0.856
Current Smokers, n (%) 597 (55 %) 188 (59 %) 409 (53 %) 0.056
Medical history     
HTN, n (%) 734 (67 %) 206 (65 %) 528 (68 %) 0.284
T2DM, n (%) 463 (42 %) 147 (46 %) 316 (41 %) 0.098
MetS, n (%)     
Hypertriglyceridemia, n (%) 446 (41 %) 202 (64 %) 244 (32 %) <0.001*
Hypercholesterolemia, n (%) 613 (56 %) 199 (63 %) 414 (53 %) 0.002*
Previous MI, n (%) 179 (16 %) 129 (17 %) 50 (16 %) 0.708
Previous Stroke, n (%) 109 (10 %) 39 (12 %) 70 (9 %) 0.105
Number of components of Mets     
0 36 (3 %) 6 (2 %) 30 (4 %) 0.095
1 142 (13 %) 26 (8 %) 116 (15 %) 0.002*
2 274 (25 %) 59 (19 %) 215 (28 %) 0.001*
3 296 (27 %) 95 (30 %) 201 (26 %) 0.183
4 240 (21 %) 85 (27 %) 155 (20 %) 0.015*
5 105 (10 %) 47 (15 %) 58 (7 %) <0.001*
Laboratory measurement     
MONO, 1012/L 0.41±0.14 0.43±0.14 0.40±0.14 0.002*
eGFR 91.4±16.89 91.2±18.15 91.4±16.36 0.693
CREA, mmol/L 78.3±19.61 79.2±21.28 78.0±18.89 0.636
UREA, mmol/L 5.6±1.83 5.8±1.90 5.5±1.80 0.092
UA, mmol/L 355.4±94.97 369.8±97.57 349.6±93.32 <0.001
FBG, mmol/L 5.88 (5.11-7.25) 6.23 (5.22-8.10) 5.75 (5.06-7.00) <0.001*
GA, % 14.4 (13.0-17.2) 14.5 (12.9-18.0) 14.4 (13.0-16.8) 0.455
HbA1C, % 6.1 (5.7-6.9) 6.2 (5.8-7.4) 6.1 (5.7-6.8) 0.001*
TyG index 9.3±0.65 9.3±0.65 8.8±0.53 <0.001
TC, mmol/L 3.9±0.99 4.1±1.07 3.8±0.94 <0.001
TG, mmol/L 1.7±0.91 2.2±1.11 1.6±0.73 <0.001
HDL-C, mmol/L 1.0±0.25 1.0±0.24 1.1±0.25 <0.001*
LDL-C, mmol/L 2.3±0.88 2.4±0.95 2.2±0.85 0.005*
Non-HDL-C, mmol/L 2.9±0.97 3.1±1.05 2.8±0.91 <0.001*
Hs CRP, mg/L 1.02 (0.52-2.64) 1.13 (0.68-3.16) 0.97 (0.48-2.38) 0.002*
LVEF, % 59.3±8.59 59.0±8.91 59.5±8.46 0.343
Cardiovascular Medication     
Antiplatelet therapy, n (%) 940 (86 %) 274 (86 %) 666 (86 %) 0.921
β-blockers, n (%) 660 (60 %) 200 (63 %) 460 (59 %) 0.277
ACEI/ARB, n (%) 360 (33 %) 112 (35 %) 248 (32 %) 0.304
Statins, n (%) 902 (83 %) 267 (84 %) 635 (82 %) 0.423
CCB, n (%) 305 (28 %) 80 (25 %) 225 (29 %) 0.195
Severity of CAD     0.912
One-vessel disease, n (%) 154 (14 %) 43 (14 %) 111 (14 %) 0.775
Two-vessel disease, n (%) 313 (29 %) 90 (28 %) 223 (29 %) 0.941
Three-vessel disease, n (%) 626 (57 %) 185 (58 %) 441 (57 %) 0.737
CTO related artery     0.078
RCA 528 (48 %) 139 (44 %) 389 (50 %) 0.054
LCX 192 (18 %) 55 (17 %) 137 (18 %) 0.93
LAD 373 (34 %) 124 (39 %) 249 (32 %) 0.035*
Grade of collaterals     
0 69 (6 %) 69 (22 %) -  
1 249 (23 %) 249 (78 %) -  
2 551 (50 %) - 551 (71 %)  
3 224 (21 %) - 224 (29 %)  
ISR-CTO 104 (10 %) 37 (12 %) 67 (9 %) 0.14
  1. * Indicates the difference between two groups was statistically significant
  2. Abbreviations: BMI Body mass index, SBP Systolic blood pressure, DBP Diastolic blood pressure, HTN Hypertension, T2DM Type2 diabetes mellitus, PCI Percutaneous coronary intervention, MetS Metabolic syndrome, MI Myocardial infarction, MONO Monocyte count, eGFR Estimated glomerular filtration rate, CREA Creatinine, UREA Urea, UA Uric acid, FPG Fasting plasma glucose, GA Glycated albumin, HbA1c Glycosylated hemoglobin A1c, TyG index Triglyceride glucose index, TC Total cholesterol, TG Triglyceride, HDL-C High-density lipoprotein cholesterol, LDL-C Low-density lipoprotein cholesterol, non HDL-C Non high-density lipoprotein cholesterol, hs-CRP High-sensitivity C-reactive protein, LVEF Left ventricular ejection fraction, ACEI/ARB Angiotensin-converting enzyme inhibitors / angiotensin receptor blockers, CCB Calcium channel blocker, CAD Coronary artery disease, CTO Chronic total lesion, RCA Right coronary artery, LCX Left circumflex coronary artery, LAD Left anterior descending artery, ISR In-stent restenosis