Medium & long-chain acylcarnitine’s relation to lipid metabolism as potential predictors for diabetic cardiomyopathy: a metabolomic study

Table 3 Factor and their loadings derived by 25 acylcarnitine metabolites

*Variables*	*Factor 1*	*Factor 2*	*Factor 3*	*Factor 4*	*Factor 5*	*Factor 6*
C14	0.945	−0.098	−0.070	0.066	0.019	0.002
C12	0.881	0.036	0.029	0.335	0.003	−0.010
C14DC	0.735	0.357	0.114	−0.109	0–.051	0.229
C14-OH	0.729	0.374	0.028	0.207	0.223	0.011
C20	0.687	0.515	0.047	0.123	0.192	0.047
C18	0.624	0.271	0.416	−0.046	0.137	−0.183
C16:1-OH	0.603	0.372	0.389	−0.067	0.276	0.159
C26	0.251	0.739	0.235	0.420	0.065	−0.156
C14:1	0.268	0.735	0.227	0.422	0.049	−0.133
C24	0.324	0.706	0.065	0.107	0.141	0.094
C22	0.219	0.696	0.070	−0.003	0.251	0.284
C4-OH	0.030	0.667	0.485	0.038	0.209	0.167
C2	0.040	0.105	0.837	0.180	0.121	−0.023
C3	0.122	0.025	0.777	0.058	0.250	0.134
C4	−0.093	0.349	0.741	0.169	0.159	0.222
C16	0.462	0.289	0.605	0.062	0.146	−0.264
C8	0.126	0.215	0.091	0.905	0.130	−0.044
C6	0.027	−0.031	0.136	0.842	−0.077	0.277
C10	0.147	0.357	0.169	0.782	0.240	−0.229
C5-OH	0.105	0.215	0.156	0.013	0.849	0.076
C4DC	0.086	0.331	0.213	0.073	0.747	−0.177
C0	0.082	−0.110	0.452	0.170	0.681	0.051
C5:1	0.049	0.466	0.082	0.076	0.476	0.306
C5	−0.022	0.125	0.493	0.094	0.109	0.645
C16-OH	0.490	0.211	−0.045	− 0.045	−0.055	0.529

Principal component analysis of extracted factors from 25 acylcarnitines according to eigenvalue > 1, lithotripsy, and cumulative variance. To maximize the variance difference of each factor, varimax rotation is used. Each black labeled acylcarnitine in each column defines a factor in the corresponding column (factor 1: C14, C12, C14DC, C14-OH, C20, C18, C16:1-OH; factor 2: C26, C14:1, C24, C22, C4-OH; factor 3: C2, C3, C4, C16; factor4: C8, C6, C10; factor 5: C5-OH, C4DC, C0; and factor 6: C5, C16-OH)

ISSN: 1476-511X