Lipids in Health and Disease

Table 1 Mean ± SD plasma levels of PGE2-EP2, COX-2, and α-Syn in patients with autism compared to healthy controls

From: Alpha-Synuclein, cyclooxygenase-2 and prostaglandins-EP2 receptors as neuroinflammatory biomarkers of autism spectrum disorders: Use of combined ROC curves to increase their diagnostic values

Parameters	Groups	N	Min.	Max.	Mean ± SD	Percent change	P value
PGE2-EP2 (pg/ml)	Control	40	413.02	4987.98	2131.01 ± 1497.85	100.00	0.001
PGE2-EP2 (pg/ml)	Patient	40	1450.20	8635.27	4794.25 ± 1762.30	224.98	0.001
COX-2 (ng/ml)	Control	40	0.91	8.64	3.28 ± 2.00	100.00	0.001
COX-2 (ng/ml)	Patient	40	0.05	20.57	7.89 ± 5.80	240.94	0.001
α-Syn (pg/ml)	Control	40	8.20	31.54	17.19 ± 5.96	100.00	0.124
α-Syn (pg/ml)	Patient	40	8.51	40.66	15.54 ± 6.75	90.39	0.124

Data were compared between groups using the Mann–Whitney test

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