Alpha-Synuclein, cyclooxygenase-2 and prostaglandins-EP2 receptors as neuroinflammatory biomarkers of autism spectrum disorders: Use of combined ROC curves to increase their diagnostic values

Table 2 Multiple regression analysis using the stepwise method for PGE2-EP2, COX-2, and α-Syn as dependent variables

Dependent variable	Predictive Variable	Coefficient	S.E.	P value	Adjusted R²	95% CI
Dependent variable	Predictive Variable	Coefficient	S.E.	P value	Adjusted R²	Lower	Upper
PGE2-EP2	COX-2	210.550	66.861	0.002	0.121	76.981	344.120
COX-2	PGE2-EP2	0.001	0.000	0.002	0.121	0.000	0.001
	PGE2-EP2 α-Syn	0.001	0.000	0.893	0.167	0.000	0.001
	PGE2-EP2 α-Syn	0.143	0.067	0.003	0.167	0.009	0.277
α-Syn	COX-2	0.451	0.204	0.031	0.056	0.043	0.858

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