From: Circulating ANGPTL3 and ANGPTL4 levels predict coronary artery atherosclerosis severity
Variable | The stenosis of coronary artery | χ, t, Z value | P value | |
---|---|---|---|---|
≥ 10% (n = 208) | <  10% (n = 97) | |||
Age, years | 67.52 ± 9.91 | 61.86 ± 9.59 | 3.615 | < 0.001 |
Sex (male), % | 55.8 (116/208) | 42.3 (41/97) | 4.827 | 0.028 |
Smokers, % | 39.4 (82/208) | 25.8 (25/97) | 5.412 | 0.020 |
Alcohol consumers, % | 22.6 (47/208) | 18.6 (18/97) | 0.644 | 0.422 |
BMI ≥ 24 kg/m2, % | 63.2 (129/204) | 50.5 (48/95) | 4.334 | 0.043 |
CHD family history, % | 61.5 (128/208) | 53.6 (52/97) | 2.191 | 0.212 |
Diabetes mellitus, % | 26.4 (55/208) | 11.3 (11/97) | 8.897 | 0.003 |
Hypertension, % | 65.9 (137/208) | 48.5 (47/97) | 8.379 | 0.004 |
NYHA class III/ IV, % | 10.1 (21/208) | 3.1 (3/97) | 6.491 | 0.011 |
Atrial fibrillation, % | 9.1 (19/208) | 7.2 (7/97) | 0.312 | 0.576 |
Hypolipidemic drugs, % | 18.2 (37/203) | 25.0 (24/96) | 1.841 | 0.175 |
Aspirin use, % | 91.8 (191/208) | 93.8 (91/97) | 0.375 | 0.540 |
Hypoglycemic drugs, % | 22.1 (46/208) | 9.3 (9/97) | 7.375 | 0.007 |
Antihypertensive drugs, % | 59.6 (124/208) | 41.2 (40/97) | 8.988 | 0.003 |
Blood glucose, mmol/L | 6.04 ± 2.08 | 5.78 ± 2.28 | 0.006 | 0.370 |
GHb, % | 6.43 ± 1.13 | 6.98 ± 6.92 | 4.976 | 0.350 |
Myoglobin, μg/L | 44.71 ± 49.66 | 31.41 ± 22.94 | 9.192 | 0.002 |
cTnI, ng/mL | 0.13 ± 1.01 | 0.03 ± 0.09 | −0.349 | 0.727 |
LVEF, % | 61.32 ± 6.98 | 61.08 ± 6.24 | 0.410 | 0.800 |
LVEDP, mmHg | 6.16 ± 2.31 | 6.63 ± 2.06 | 2.202 | 0.140 |
Heart Rate, bpm | 75.39 ± 16.17 | 76.98 ± 17.05 | 1.317 | 0.433 |
BNP, pg/mL | 155.09 ± 354.50 | 171.21 ± 516.34 | −1.695 | 0.090 |
Lipoprotein(a), g/L | 0.16 ± 0.16 | 0.16 ± 0.19 | 3.162 | 0.728 |
apoE, mg/dL | 4.52 ± 1.91 | 4.52 ± 1.54 | 0.382 | 0.997 |
FFA, mmol/L | 0.51 ± 0.21 | 0.47 ± 0.20 | 1.226 | 0.214 |
LDL-C, mmol/L | 2.74 ± 0.91 | 2.92 ± 0.82 | 0.631 | 0.118 |
HDL-C, mmol/L | 1.07 ± 0.31 | 1.11 ± 0.33 | 0.000 | 0.303 |
Triglycerides, mmol/L | 1.68 ± 0.99 | 1.60 ± 0.97 | 0.700 | 0.543 |
apoA-I, g/L | 1.12 ± 0.20 | 1.14 ± 0.22 | 0.050 | 0.447 |
apoB, g/L | 0.85 ± 0.25 | 0.94 ± 0.73 | 0.842 | 0.175 |
apoA-I/apoB | 1.48 ± 0.52 | 1.45 ± 0.41 | 0.777 | 0.709 |
ANGPTL3, ng/mL | 51.71 ± 52.67 | 24.65 ± 10.32 | −8.027 | < 0.001 |
ANGPTL4, ng/mL | 454.66 ± 269.05 | 875.49 ± 961.15 | −4.683 | < 0.001 |