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Table 2 Demographic, clinical and biochemical characteristics of the study sample according to the results of coronary arteriography

From: Circulating ANGPTL3 and ANGPTL4 levels predict coronary artery atherosclerosis severity

Variable

The stenosis of coronary artery

χ, t, Z value

P value

≥ 10% (n = 208)

<  10% (n = 97)

Age, years

67.52 ± 9.91

61.86 ± 9.59

3.615

< 0.001

Sex (male), %

55.8 (116/208)

42.3 (41/97)

4.827

0.028

Smokers, %

39.4 (82/208)

25.8 (25/97)

5.412

0.020

Alcohol consumers, %

22.6 (47/208)

18.6 (18/97)

0.644

0.422

BMI ≥ 24 kg/m2, %

63.2 (129/204)

50.5 (48/95)

4.334

0.043

CHD family history, %

61.5 (128/208)

53.6 (52/97)

2.191

0.212

Diabetes mellitus, %

26.4 (55/208)

11.3 (11/97)

8.897

0.003

Hypertension, %

65.9 (137/208)

48.5 (47/97)

8.379

0.004

NYHA class III/ IV, %

10.1 (21/208)

3.1 (3/97)

6.491

0.011

Atrial fibrillation, %

9.1 (19/208)

7.2 (7/97)

0.312

0.576

Hypolipidemic drugs, %

18.2 (37/203)

25.0 (24/96)

1.841

0.175

Aspirin use, %

91.8 (191/208)

93.8 (91/97)

0.375

0.540

Hypoglycemic drugs, %

22.1 (46/208)

9.3 (9/97)

7.375

0.007

Antihypertensive drugs, %

59.6 (124/208)

41.2 (40/97)

8.988

0.003

Blood glucose, mmol/L

6.04 ± 2.08

5.78 ± 2.28

0.006

0.370

GHb, %

6.43 ± 1.13

6.98 ± 6.92

4.976

0.350

Myoglobin, μg/L

44.71 ± 49.66

31.41 ± 22.94

9.192

0.002

cTnI, ng/mL

0.13 ± 1.01

0.03 ± 0.09

−0.349

0.727

LVEF, %

61.32 ± 6.98

61.08 ± 6.24

0.410

0.800

LVEDP, mmHg

6.16 ± 2.31

6.63 ± 2.06

2.202

0.140

Heart Rate, bpm

75.39 ± 16.17

76.98 ± 17.05

1.317

0.433

BNP, pg/mL

155.09 ± 354.50

171.21 ± 516.34

−1.695

0.090

Lipoprotein(a), g/L

0.16 ± 0.16

0.16 ± 0.19

3.162

0.728

apoE, mg/dL

4.52 ± 1.91

4.52 ± 1.54

0.382

0.997

FFA, mmol/L

0.51 ± 0.21

0.47 ± 0.20

1.226

0.214

LDL-C, mmol/L

2.74 ± 0.91

2.92 ± 0.82

0.631

0.118

HDL-C, mmol/L

1.07 ± 0.31

1.11 ± 0.33

0.000

0.303

Triglycerides, mmol/L

1.68 ± 0.99

1.60 ± 0.97

0.700

0.543

apoA-I, g/L

1.12 ± 0.20

1.14 ± 0.22

0.050

0.447

apoB, g/L

0.85 ± 0.25

0.94 ± 0.73

0.842

0.175

apoA-I/apoB

1.48 ± 0.52

1.45 ± 0.41

0.777

0.709

ANGPTL3, ng/mL

51.71 ± 52.67

24.65 ± 10.32

−8.027

< 0.001

ANGPTL4, ng/mL

454.66 ± 269.05

875.49 ± 961.15

−4.683

< 0.001

  1. CHD coronary heart diseases, NYHA New York Heart Association (2013 ACC/AHA guidelines), GHb glycosylated hemoglobin, LVEF left ventricular ejection fraction, LVEDP left ventricular end diastolic pressure, BNP B-type natriuretic peptide, apo apolipoprotein, FFA free fatty acid, LDL-C low-density lipoprotein-cholesterol, HDL-C high-density lipoprotein-cholesterol, BMI body mass index, ANGPTL angiopoietin-like proteins;