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Table 3 ANGPTL3, ANGPTL4 and lipids levels of the study sample according to the degree of coronary artery stenosis

From: Circulating ANGPTL3 and ANGPTL4 levels predict coronary artery atherosclerosis severity

Variable

The degree of coronary artery stenosis

<  10%

10-50%

50-75%

≥ 75%

F or Z value

P value

t or Z value

P1 value

ANGPTL3, ng/mL

24.66 ± 10.32

51.90 ± 68.68

51.56 ± 31.59

51.56 ± 38.81

67.073

< 0.001

−6.106

< 0.001

ANGPTL4, ng/mL

875.5 ± 961.2

465.4 ± 268.6

472.6 ± 309.1

409.0 ± 202.8

22.733

< 0.001

−3.731

< 0.001

Triglycerides, mmol/L

1.60 ± 0.97

1.67 ± 0.94

1.72 ± 1.10

1.65 ± 0.92

0.176

0.913

1.005

0.658

LDL-C, mmol/L

2.92 ± 0.81

2.72 ± 0.86

2.69 ± 0.99

2.86 ± 0.90

1.179

0.318

0.207

0.119

HDL-C, mmol/L

1.11 ± 0.33

1.12 ± 0.34

1.01 ± 0.26

1.03 ± 0.32

1.938

0.124

0.110

0.798

apoA-I, g/L

1.14 ± 0.22

1.14 ± 0.18

1.10 ± 0.19

1.09 ± 0.25

0.721

0.540

0.297

0.930

apoB, g/L

0.94 ± 0.73

0.86 ± 0.25

0.83 ± 0.26

0.85 ± 0.24

0.661

0.577

0.400

0.441

apoA-I/apoB

1.45 ± 0.41

1.49 ± 0.48

1.52 ± 0.58

1.42 ± 0.48

0.323

0.809

0.135

0.667

apoE, mg/dL

4.52 ± 1.54

4.45 ± 1.24

4.73 ± 2.77

4.36 ± 1.29

0.333

0.801

0.462

0.776

Lipoprotein(a), g/L

0.16 ± 0.19

0.15 ± 0.15

0.15 ± 0.16

0.19 ± 0.19

0.554

0.646

4.016

0.451

FFA, mmol/L

0.47 ± 0.20

0.47 ± 0.17

0.47 ± 0.21

0.63 ± 0.23

6.429

< 0.001

0.006

0.964

  1. P, comparison among the four groups; P1, comparison between non-stenosis group and stenosis 10 - 50% group; ANGPTL angiopoietin-like proteins, LDL-C low-density lipoprotein-cholesterol, HDL-C high-density lipoprotein-cholesterol, apo apolipoprotein, FFA free fatty acid; ANGPTL3,4 values for Mann-Whitney U-test; lipid variables values for one-way ANOVA and A Student’s t-test