Skip to main content

Table 6 Odds ratios from logistic regression models predicting at-risk levels of serum lipids by APOE ε2 and ε4 carriers in middle-aged (40+) and elderly (60+) males or females

From: The effects of genetic polymorphisms of APOE on circulating lipid levels in middle-aged and elderly chinese Fujian Han population: toward age- and sex-personalized management

 

Serum

ε2 carrier

ε4 carrier

Outcome

Pvalue

OR (95% CI)

Pvalue

OR (95% CI)

Male

TC (≥5.2)

0.080

0.494(0.224,1.088)

0.701

0.824(0.411,1.817)

40+

TG (≥1.7)

0.806

0.909(0.425,1.945)

0.431

0.726(0.327,1.612)

 

HDLC (<1.0)

0.878

1.078(0.414,2.805)

0.065

0.466(0.207,1.057)

 

LDL-C (≥3.4)

0.001**

0.165(0.061,0.444)

0.112

0.539(0.252,1.155)

65+

TC (≥5.2)

0.608

0.730(0.220,2.430)

0.702

0.806(0.267,2.434)

 

TG (≥1.7)

0.072

3.556(0.894,14.135)

0.346

2.113(0.217,5.711)

 

HDLC (<1.0)

0.210

3.303(0.471,10.723)

0.658

1.357(0.445,10.020)

 

LDL-C (≥3.4)

0.034*

0.204(0.060,0.916)

0.953

0.969(0.339,2.768)

Female

TC (≥5.2)

0.985

1.009(0.424,2.401)

0.664

0.836(0.371,1.880)

40+

TG (≥1.7)

0.374

0.386(0.048,3.139)

0.290

1.855 (0.591,5.822)

 

HDLC (<1.0)

0.998

0(----, ----)

0.601

0.523(0.046,5.965)

 

LDL-C (≥3.4)

0.109

0.598(0.339,1.551)

0.746

1.143(0.509,2.564)

65+

TC (≥5.2)

0.954

1.037(0.297,3.616)

0.944

1.036(0.373,2.886)

 

TG (≥1.7)

0.602

0.646 (0.125,3.333)

0.046*

2.937(1.026,8.464)

 

HDLC (<1.0)

0.203

0.288(0.043,1.954)

0.195

0.327(0.060,1.774)

 

LDL-C (≥3.4)

0.668

0.750(0.201,2.796)

0.698

1.227(0.437,3.448)

  1. OR odds ratio; CI confidence interval. The confounding factors including age, BMI, education, smoking, alcohol drinking, and physical activity were critically adjusted. TC Total cholesterol, TG Triglyceride, HDL-C High density lipoprotein cholesterol, LDL-C Low density lipoprotein cholesterol. ApoA1 apolipoproteinA1, ApoB apolipoprotein B
  2. The diagnostic criteria for dyslipidemia: high TC (≥5.2 m mol/L), high TG (≥1.7 m mol/L), high LDL-C (≥3.4 m mol/L), and low HDL-C (<1.0 m mol/L)
  3. *P<0.05, **P<0.01, VS ε3 carriers