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Table 2 Associations among the four lipids with treatment response

From: Levels of pretreatment blood lipids are prognostic factors in advanced NSCLC patients treated with anlotinib

Response

n

%

TG

TC

LDL

HDL

< 1.82

≥1.82

P value

< 4.77

≥4.77

P value

< 2.965

≥2.965

P value

< 1.095

≥1.095

P value

CR

0

0

            

PR

6

4

5

(3.6%)

1

(0.7%)

0.002

4

(2.9%)

2

(1.4%)

0.000

5

(3.6%)

1

(0.7%)

0.000

2

(1.4%)

4

(2.9%)

0.218

SD

94

68.6

76

(55.5%)

18

(13.1%)

 

67

(48.9%)

27

(19.7%)

 

73

(53.3%)

21

(15.3%)

 

52

(38%)

42

(30.1%)

 

PD

37

27

19

(13.9%)

18

(13.1%)

 

8

(5.8%)

29

(21.2%)

 

12

(8.8%)

25

(18.2%)

 

15

(10.9%)

22

(16.1%)

 

ORR

6

4

            

DCR

100

72.6

81

(59.1%)

19

(13.9%)

0.000

71

(51.8%)

29

(21.2%)

0.000

78

(56.9%)

22

(16.1%)

0.000

54

(39.4%)

46

(33.6%)

0.162

  1. The unit of measurement for lipids is mmol/L
  2. CR complete response, PR partial response, SD stable disease, PD progressive disease, ORR overall response rate, DCR disease control rate, TG triglyceride, TC total cholesterol, LDL low density lipoprotein, HDL high density lipoprotein