Fig. 6From: 15-Lipoxygenase and its metabolites in the pathogenesis of breast cancer: A double-edged swordThe relevance of 15-LOX and the oxidative stress in breast cancer cell growth. The reduction in the expression level of 15-LOX-1 is associated with a decrease in the level of ROS and reduced breast cancer cell death [74]. Also, 15-LOX-1 activation-induced breast cancer cell apoptosis might occur through the generation of ROS [75]Back to article page