Table 2 Definitions of stroke progression and in-hospital complications
Complications | Definitions |
|---|---|
Stroke progression | The patients whose NIHSS score increased more than two points after hospitalization. |
Pneumonia | Presented at least 3 of the following manifestations: new or aggravated cough and expectoration; increased respiratory rate (≥22 times/min); fever (temperature>38℃); peripheral blood WBC count decreased (<4 × 109/L), or increased (>11 × 109/L), or increased neutrophil ratio; Auscultatory respiratory moist rales; abnormal chest radiology (patchy infiltration, lobar consolidation, or pleural effusion). |
Urinary tract infection | Clinical symptoms of urinary tract infection combined with an increase in white blood cell and bacterial counts on routine urine tests, or bacterial growth in urine culture. |
Hemorrhagic transformation | Hemorrhage in the infarct area or other parts of the brain parenchyma. |
Gastrointestinal bleeding | Having coffee-ground emesis, hematemesis, and blood in nasogastric tube, melena, or blood in rectum, accompanied by blood routine tests showing a decrease in hemoglobin than before, or vomit, fecal occluded blood test is positive. |
Seizures | Previously nonepileptic patients presented focal seizure and/or generalized seizure. |
Renal insufficiency | Estimated glomerular filtration rate (eGFR)<60 mL/min. |