Table 1 Baseline and demographic characteristics of lean and obese cohorts
Parameters | Lean | Obese | P Value |
|---|---|---|---|
N = 20 | N = 98 | ||
Mean ± SD | Mean ± SD | ||
Age (years) | 36.19 ± 9.83 | 35.13 ± 9.83 | 0.508 |
Sex (M : F) | 1 : 1.9 | 1 : 2.5 | |
BMI (kg/m2) | 24.66 ± 3.24 | 45.59 ± 8.25 | < 0.005* |
Waist circ. (cm) | 72.64 ± 17.26 | 130.99 ± 12.72 | < 0.005* |
Hip circ. (cm) | 96.05 ± 5.55 | 131.41 ± 10.01 | < 0.005* |
Cholesterol (mg/dL) | 185.02 ± 73.24 | 187.69 ± 39.13 | 0.815 |
Triglycerides (mg/dL) | 118.12 ± 80.97 | 117.09 ± 75.15 | 0.956 |
HDL (mg/dL) | 50.35 ± 14.15 | 46.56 ± 13.85 | 0.269 |
LDL (mg/dL) | 112.69 ± 57.20 | 121.92 ± 31.99 | 0.315 |
FBS (mg/dL) | 94.67 ± 9.62 | 119.70 ± 39.30 | 0.006* |
Insulin (mcIU/mL) | 8.84 ± 2.97 | 17.89 ± 10.65 | < 0.005* |
HOMA-IR | 2.09 ± 0.81 | 5.31 ± 3.63 | < 0.005* |
Albumin (g/L) | 3.71 ± 0.46 | 3.51 ± 0.40 | 0.052 |
T-protein (g/L) | 7.08 ± 0.55 | 7.28 ± 0.49 | 0.115 |
T-bilirubin (µmol/L) | 0.55 ± 0.35 | 0.47 ± 0.37 | 0.417 |
LDH (IU/L) | 175.80 ± 54.66 | 197.37 ± 50.91 | 0.0913 |
AST (IU/L) | 29.35 ± 23.31 | 32.25 ± 31.66 | 0.699 |
ALT (IU/L) | 66.60 ± 89.65 | 47.75 ± 44.54 | 0.162 |
ALP (IU/L) | 72.35 ± 32.08 | 83.63 ± 27.93 | 0.111 |
GGT (IU/L) | 56.35 ± 47.75 | 44.50 ± 32.01 | 0.171 |
PT (IU/L) | 12.32 ± 0.78 | 12.24 ± 0.87 | 0.688 |
TSH (mIU/L) | 1.46 ± 0.92 | 2.06 ± 1.17 | 0.038* |