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Table 1 Baseline and demographic characteristics of lean and obese cohorts

From: Insulin resistance induced by de novo pathway–generated C16-ceramide is associated with type 2 diabetes in an obese population

Parameters Lean Obese P Value
N = 20  N = 98
Mean ± SD Mean ± SD
Age (years) 36.19 ± 9.83 35.13 ± 9.83 0.508
Sex (M : F) 1 : 1.9 1 : 2.5  
BMI (kg/m2) 24.66 ± 3.24 45.59 ± 8.25 < 0.005*
Waist circ. (cm) 72.64 ± 17.26 130.99 ± 12.72 < 0.005*
Hip circ. (cm) 96.05 ± 5.55 131.41 ± 10.01 < 0.005*
Cholesterol (mg/dL) 185.02 ± 73.24 187.69 ± 39.13 0.815
Triglycerides (mg/dL) 118.12 ± 80.97 117.09 ± 75.15 0.956
HDL (mg/dL) 50.35 ± 14.15 46.56 ± 13.85 0.269
LDL (mg/dL) 112.69 ± 57.20 121.92 ± 31.99 0.315
FBS (mg/dL) 94.67 ± 9.62 119.70 ± 39.30 0.006*
Insulin (mcIU/mL) 8.84 ± 2.97 17.89 ± 10.65 < 0.005*
HOMA-IR 2.09 ± 0.81 5.31 ± 3.63 < 0.005*
Albumin (g/L) 3.71 ± 0.46 3.51 ± 0.40 0.052
T-protein (g/L) 7.08 ± 0.55 7.28 ± 0.49 0.115
T-bilirubin (µmol/L) 0.55 ± 0.35 0.47 ± 0.37 0.417
LDH (IU/L) 175.80 ± 54.66 197.37 ± 50.91 0.0913
AST (IU/L) 29.35 ± 23.31 32.25 ± 31.66 0.699
ALT (IU/L) 66.60 ± 89.65 47.75 ± 44.54 0.162
ALP (IU/L) 72.35 ± 32.08 83.63 ± 27.93 0.111
GGT (IU/L) 56.35 ± 47.75 44.50 ± 32.01 0.171
PT (IU/L) 12.32 ± 0.78 12.24 ± 0.87 0.688
TSH (mIU/L) 1.46 ± 0.92 2.06 ± 1.17 0.038*
  1. *P< 0.05