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Table 2 Baseline and demographic characteristics of obese non-diabetic and obese diabetic cohorts

From: Insulin resistance induced by de novo pathway–generated C16-ceramide is associated with type 2 diabetes in an obese population

Parameters

Obese-NDM

Obese-DM

P Value

N = 66

 N = 32

Mean ± SD

Mean ± SD

Age (years)

33.56 ± 9.76

39.03 ± 9.97

0.011*

Sex (M : F)

1 : 2.88

1 : 1.90

 

BMI (kg/m2)

44.77 ± 7.56

47.30 ± 9.40

0.155

Waist circ. (cm)

128.65 ± 12.56

135.81 ± 11.84

0.008*

Hip circ. (cm)

129.55 ± 9.66

135.24 ± 9.77

0.008*

Cholesterol (mg/dL)

187.79 ± 34.10

187.49 ± 48.51

0.972

Triglycerides (mg/dL)

111.87 ± 65.55

127.85 ± 92.12

0.326

HDL (mg/dL)

48.39 ± 12.60

42.80 ± 15.68

0.060

LDL (mg/dL)

121.82 ± 29.60

122.11 ± 36.96

0.967

FBS (mg/dL)

99.65 ± 13.02

161.07 ± 43.06

< 0.005*

Insulin (mcIU/mL)

17.12 ± 10.50

19.46 ± 10.95

0.310

HOMA-IR

4.20 ± 2.63

7.62 ± 4.30

< 0.005*

Albumin (g/L)

3.49 ± 0.42

3.54 ± 0.34

0.566

T-protein (g/L)

7.25 ± 0.45

7.35 ± 0.57

0.330

T-bilirubin (µmol/L)

0.42 ± 0.24

0.58 ± 0.55

0.043*

LDH (IU/L)

194.97 ± 50.31

202.32 ± 52.57

0.506

AST (IU/L)

25.52 ± 15.07

46.45 ± 48.42

< 0.005*

ALT (IU/L)

37.98 ± 30.76

67.90 ± 60.01

< 0.005*

ALP (IU/L)

76.45 ± 20.72

98.43 ± 34.72

< 0.005*

GGT (IU/L)

36.68 ± 23.40

60.63 ± 40.73

< 0.005*

PT (IU/L)

12.21 ± 0.75

12.29 ± 1.09

0.671

TSH (IU/L)

2.11 ± 1.25

1.97 ± 1.00

0.572

  1. *P< 0.05