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Table 2 Baseline and demographic characteristics of obese non-diabetic and obese diabetic cohorts

From: Insulin resistance induced by de novo pathway–generated C16-ceramide is associated with type 2 diabetes in an obese population

Parameters Obese-NDM Obese-DM P Value
N = 66  N = 32
Mean ± SD Mean ± SD
Age (years) 33.56 ± 9.76 39.03 ± 9.97 0.011*
Sex (M : F) 1 : 2.88 1 : 1.90  
BMI (kg/m2) 44.77 ± 7.56 47.30 ± 9.40 0.155
Waist circ. (cm) 128.65 ± 12.56 135.81 ± 11.84 0.008*
Hip circ. (cm) 129.55 ± 9.66 135.24 ± 9.77 0.008*
Cholesterol (mg/dL) 187.79 ± 34.10 187.49 ± 48.51 0.972
Triglycerides (mg/dL) 111.87 ± 65.55 127.85 ± 92.12 0.326
HDL (mg/dL) 48.39 ± 12.60 42.80 ± 15.68 0.060
LDL (mg/dL) 121.82 ± 29.60 122.11 ± 36.96 0.967
FBS (mg/dL) 99.65 ± 13.02 161.07 ± 43.06 < 0.005*
Insulin (mcIU/mL) 17.12 ± 10.50 19.46 ± 10.95 0.310
HOMA-IR 4.20 ± 2.63 7.62 ± 4.30 < 0.005*
Albumin (g/L) 3.49 ± 0.42 3.54 ± 0.34 0.566
T-protein (g/L) 7.25 ± 0.45 7.35 ± 0.57 0.330
T-bilirubin (µmol/L) 0.42 ± 0.24 0.58 ± 0.55 0.043*
LDH (IU/L) 194.97 ± 50.31 202.32 ± 52.57 0.506
AST (IU/L) 25.52 ± 15.07 46.45 ± 48.42 < 0.005*
ALT (IU/L) 37.98 ± 30.76 67.90 ± 60.01 < 0.005*
ALP (IU/L) 76.45 ± 20.72 98.43 ± 34.72 < 0.005*
GGT (IU/L) 36.68 ± 23.40 60.63 ± 40.73 < 0.005*
PT (IU/L) 12.21 ± 0.75 12.29 ± 1.09 0.671
TSH (IU/L) 2.11 ± 1.25 1.97 ± 1.00 0.572
  1. *P< 0.05