Delta-5® oil, containing the anti-inflammatory fatty acid sciadonic acid, improves skin barrier function in a skin irritation model in healthy female subjects

Table 2 Redness categorical data evaluated in Delta-5 oil-treated and untreated groups at various time points

Scores/Days	D0*	D1	D3	D7	D28
	Damaged Untreated Score % of Categories
5–7	14	57	29	0	0
2–4	57	14	43	29	0
0–1	29	29	29	71	100
> 0	100	100	100	86	14
0	0	0	0	14	86
	Damaged Treated Score % of Categories
5–7	0	43	14	0	0
2–4	57	14	43	0	0
0–1	43	43	43	100	100
> 0	86	86	71	71	0
0	14	14	29	29	100

Redness (Visual Expert Grading Scores; VEGS) were detected from a value of 0 (no redness detected) to a maximum observed value of 7. Categorical values represent the percentages of total subjects on each day within that range of scores. For example, on D0, 29% of subjects had a score of between 0–1, 57% had a score between 2–4, and 14% had a score of between 5–7, totaling 100%. If the total is slightly more than 100%, this is due to rounding errors. The last two rows for untreated and Delta-5 treated, show the groupings as 0 (no redness detected), or > 0 (redness detected). No statistics were applied to this type of data. D0* represents the measurement of redness immediately after application of SLS at baseline. D1, D3, D7, and D28 represent the days after application of SLS. Treatment with Delta-5 oil began just after D1, so D3 represents 2 days treatment with Delta-5. No redness measurements were made on D2

ISSN: 1476-511X