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Table 3 Adjusted hazard ratios and 95% confidence intervals for prediabetes risk associated with the LDL:HDL ratio in different test populations: sensitivity analysis

From: Association of LDL:HDL ratio with prediabetes risk: a longitudinal observational study based on Chinese adults

   LDL:HDL ratio quartiles  
No.of subjects LDL:HDL ratio Q1 Q2 Q3 Q4 P-trend
Sensitivity-1 110,838 1.09 (1.01, 1.18) Ref 1.34 (1.19, 1.50) 1.44 (1.27, 1.64) 1.48 (1.26, 1.74) < 0.0001
Sensitivity-2 95,517 1.09 (1.04, 1.14) Ref 1.45 (1.36, 1.55) 1.58 (1.47, 1.71) 1.57 (1.41, 1.73) < 0.0001
Sensitivity-3 85,186 1.07 (1.01, 1.13) Ref 1.45 (1.35, 1.57) 1.58 (1.45, 1.73) 1.58 (1.41, 1.77) < 0.0001
Sensitivity-4 35,342 1.23 (1.14, 1.32) Ref 1.34 (1.22, 1.48) 1.52 (1.37, 1.69) 1.62 (1.41, 1.86) < 0.0001
  1. Abbreviations: LDL:HDL ratio low-density lipoprotein:high-density lipoprotein cholesterol ratio
  2. Note 1 (1) Sensitivity-1: including 110,838 subjects according to WHO’s diagnostic criteria for prediabetes; (2) sensitivity-2: excluding subjects with a family history of diabetes (n = 95,517); (3) sensitivity-3: excluding subjects whose SBP ≥ 140 mmHg or DBP ≥ 90 mmHg (n = 85,186); (4) sensitivity-4: excluding subjects with normal body mass index
  3. Note 2 Adjusted for sex, age, BMI, SBP, DBP, FPG, TC, TG, HDL-C, ALT, BUN and Cr