Table 2 Incidence rates and hazard ratios of cancer risk
Exposure of interest | Number of Events | Incidence Rate per 1,000 Person-years (95% CI) | Crude Hazard Ratio (95% CI) |
|---|---|---|---|
Any type of cancer | |||
General Population (reference) | 485 | 9.96 (9.11–10.9) | 1.00 |
Mutation-carrying HeFH relatives | 30 | 11.3 (7.89–16.1) | 1.18 (0.81–1.71) |
Nonmutation-carrying HeFH relatives | 12 | 4.81 (2.73–8.47) | 0.45 (0.26–0.80) |
Comparison of relativesa | … | … | 2.39 (1.24–4.61) |
All-cause mortality | |||
General Population (reference) | 563 | 10.8 (9.98–11.8) | 1.00 |
Mutation-carrying HeFH relatives | 22 | 7.61 (5.01–11.6) | 0.70 (0.46–1.07) |
Nonmutation-carrying HeFH relatives | 18 | 7.04 (4.44–11.2) | 0.65 (0.40–1.03) |
Comparison of relativesa | … | … | 1.08 (0.58–2.02) |