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Table 5 Prospective multivariable Cox Regression Analysis of Predictive Factors for a cardiovascular death in the families group

From: Current causes of death in familial hypercholesterolemia

heFH family members CVD death HR (95% CI) CVD death HR (95% CI)a
 All 3.02 (1.90–4.79) 2.85 (1.73–4.69)
 Males 2.90 (1.59–5.29) 2.95 (1.52- 5.71)
 Females 3.20 (1.55–6.63) 3.44 (1.66–7.10)
NonheFH family members HR (95%CI) HR (95%CI)a
 All 0.81 (0.46–1.42) 0.98 (0.58–1.65)
 Males 0.79 (0.49–1.57) 0.80 (0.41–1.53)
 Females 0.95 (0.33–2.67) 1.02 (0.38–2.71)
  1. 95% CI, 95% confidence interval; HR, hazard ratio. HR (95%CI)
  2. aconfidence interval estimations calculate taking into account family clusters