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Table 1 Baseline characteristics of study participants

From: Peri-event plasma PCSK9 and hsCRP after an acute myocardial infarction correlate with early deterioration of left ventricular ejection fraction: a cohort study

 

Women

Men

Total

n=

24 (22.6%)

82 (77.4%)

106

Age

68 +/−  13

63 +/−  11.9

64.1 +/−  12.3

Time between onset of symptoms and sample (hours)

52.7 +/−  34.3

50.3 +/−  33.7

50.9 +/−  33.7

Body-mass index (Kg/m2)

25.5 +/−  5

27 +/−  4

26.7 +/−  4.3

Systolic blood pressure (mmHg)

127 +/−  24.4

133.8 +/−  25.2

132.2 +/−  25.1

Diastolic blood pressure (mmHg)

77.9 +/−  12.5

81 +/−  17.6

80.3 +/−  16.6

Heart rate (bpm)

82.4 +/−  18.1

75.6 +/−  20.5

77.1 +/−  20.1

Baseline troponin (ng/L)

3797.2 +/−  12,886

3397 +/−  10,609.3

3489.4 +/−  11,110.3

Glycated hemoglobin A1c (%)

7.0 +/−  1.7

6.6 +/−  1.3

6.7 +/−  1.4

Total cholesterol (mg/dL)

149.2 +/−  45.3

158.5 +/−  52.5

156.4 +/−  50.9

 mmol/L

3.84 +/−  1.17

4.10 +/−  1.36

4.05 +/−  1.32

HDL cholesterol (mg/dL)

30.7 +/− 17.8

27.3 +/−  9.6

28.1 +/−  11.9

 mmol/L

0.79 +/− 0.46

0.71 +/−  0.25

0.73 +/−  0.31

LDL cholesterol (mg/dL)

96.2 +/− 36.1

101.9 +/−  53.5

100.6 +/−  50.0

 mmol/L

2.49 +/−  0.93

2.64 +/−  1.39

2.61 +/−  1.30

Triglycerides (mg/dL)

111.5 +/−  47.0

146.8 +/−  99.1

138.8 +/−  91.0

 mmol/L

2.89 +/−  1.21

3.80 +/− 2.56

3.60 +/−  2.36

non-HDL cholesterol (mg/dL)

118.5 +/− 37.0

131.2 +/−  53.3

128.3 +/−  50.2

 mmol/L

3.07 +/−  0.96

3.40 +/− 1.38

3.32 +/− 1.30

hsCRP (mg/L)

22.5 +/−  29.6

26.4 +/−  24.2

25.5 +/−  25.5

Baseline plasma PCSK9 (ng/mL)

409.2 +/−  236.5

392.4 +/−  266.2

396.2 +/−  258.8

Baseline plasma NTproBNP (ng/mL)

162.5 +/− 100.4

315.2 +/−  603.9

280.6 +/−  536.3

Baseline plasma FABP3 (ng/mL)

6.3 +/− 8.6

22.3 +/−  61.4

18.6 +/−  54.5

Baseline LVEF (%)

54.0 +/−  10.7

57.4 +/−  8.5

56.6 +/− 9.1

Highest obstruction in coronary vessels (%)

59.0 +/− 40.9

79.1 +/−  31.2

74.8 +/− 34.3

Diabetes (%)

33.3%

25.6%

27.4%

Hypertension (%)

58.3%

54.9%

55.7%

Dyslipidemia (%)

45.8%

53.7%

51.9%

Prior myocardial infarction (%)

13.0%

20.7%

19.0%

History of cancer (%)

25.0%

11.0%

14.2%

Number of affected vessels (%)

 0

20.0%

5.3%

8.4%

 1

45.0%

20.0%

25.3%

 2

15.0%

36.0%

31.6%

 3

0.0%

22.7%

17.9%

 4

20.0%

13.3%

14.7%

 5

0.0%

2.7%

2.1%

Current use of statins (%)

41.7%

28.0%

31.1%

Current use of antihypertensives (%)

54.2%

47.6%

49.1%

Smoking (%)

4.2%

12.2%

10.4%

GRACE score

111 (27)

101 (23)

103 (25)

Mortality predicted by GRACE score

8.1 (7.2)

5.4 (4.0)

6.0 (5.0)

  1. Data are means +/− SD unless indicated otherwise. LVEF Left ventricular ejection fraction, hsCRP High-sensitivity C-reactive protein, PCSK9 Proprotein convertase subtilisin kexin type 9, NT-proBNP N-terminal prohormone of brain natriuretic peptide, FABP3 Heart-type fatty acid binding protein