Fig. 4
Boxplots of LC-MS metabolites that show a significant response (delta change between baseline and post-treatment) to the diets grouped by those that are either increased or decreased in the rTFA group. The identification levels of these metabolites were 1 for retinol and prostaglandin D3 and 3 for the two others. Different letters indicate significantly different values (paired Wilcoxon signed-rank Test, PFDR-adjusted < 0.05) paired. Plots show the IQR (box), the median dividing the IQR (—), with dashed line whiskers that extend to the last point included in the 1.5 x IQR range and outliers outside this range identified (o). One outlier in wTFA boxplot for 4-isopropylbenzoic acid was eliminated (baseline: 475.6, endpoint: 6464.7). This subject was however not removed from the robust statistical analysis