Skip to main content

Table 1 Baseline characteristics of subjects. Assessment after the run-in phase (week 2)

From: Molecular effects of the consumption of margarine and butter varying in trans fat composition: a parallel human intervention study

  wTFA group iTFA group rTFA group P
(n = 14) (n = 14) (n = 14)
Age (years) 56.5 (52.3, 58.8) 52.0 (46.8, 58) 51.0 (47, 56.5) 0.373
Sex (% male) 50 50 50  
BMI (kg/m2) 25.20 (21.0, 26.8) 24.60 (22.5, 28.2) 25.35 (23.8, 27.4) 0.778
Glucose (mmol/L) 4.68 (4.5, 5.0) 5.10 (4.7, 5.4) 4.73 (4.4, 5.0) 0.260
Insulin (mU/L) 5.00 (3.3, 6.3) 5.75 (3.5, 7.9) 3.65 (1.9, 4.4) 0.040*
Total cholesterol (mmol/L) 5.035 (4.6, 5.3) 4.895 (4.0, 5.6) 4.465 (4.3, 5.0) 0.338
HDL-C (mmol/L) 1.49 (1.3, 1.8) 1.36 (1.1, 1.5) 1.33 (1.2, 1.7) 0.401
LDL-C (mmol/L) 3.22 (2.8, 3.7) 3.06 (2.6, 3.8) 2.67 (2.5, 3.3) 0.193
Ox-LDL Ab (mU/ml) 254 (162, 476) 483 (347, 1394) 811 (411, 1167) 0.092
Triglycerides (mmol/L) 0.87 (0.75, 1.0) 0.89 (0.62, 1.4) 0.66 (0.58, 0.92) 0.314
Lp-a (mg/L) 0.13 (0.11, 0.35) 0.20 (0.08, 0.47) 0.12 (0.04, 0.8) 0.933
Apo A1 (g/L) 2.61 (1.3, 3.4) 2.05 (1.5, 2.4) 2.14 (1.7, 2.8) 0.457
Apo B (g/L) 0.87 (0.29, 1.23) 0.78 (0.41, 1.02) 1.05 (0.86, 1.39) 0.156
hs-CRP (mg/L) 0.6 (0.24, 1.49) 0.96 (0.7, 1.98) 0.82 (0.5, 2.09) 0.371
IL-6 (pg/ml) 0.74 (0.65, 0.98) 0.7 (0.6, 0.96) 1.09 (0.97, 1.38) 0.027*
TNFα (pg/ml) 2.40 (2, 5) 3.37 (1, 5.2) 3.81 (1.8, 7.2) 0.701
TNF-Receptor 1 (pg/ml) 798 (705, 974) 995 (941, 1103) 1197 (997, 1395) 0.007**
TNF-Receptor 2 (pg/ml) 2636 (2290, 4089) 2664 (2457, 3406) 1748 (1461, 2098) 0.033*
ELAM-1 (ng/ml) 2.5 (1.6, 3.4) 2.6 (1.2, 4.8) 5.5 (3.9, 8.2) 0.007**
Endothelin (pg/ml) 1.9 (1.6, 2.7) 2 (1.7, 2.3) 1.7 (1.3) 0.638
ICAM (ng/ml) 17.5 (10, 32.4) 19.1 (10.9, 32.2) 25.8 (20.7, 29.7) 0.274
VCAM (ng/ml) 212 (124, 320) 150 (113, 241) 286 (183, 415) 0.099
  1. Legend: Data are presented as medians and IQ1, IQ3 between brackets. Kruskall-Wallis test was used to determine significant difference between subjects in the three groups. P < 0.05: *, P < 0.01: **, P < 0.001: ***
  2. Abbreviations: Apo A1 Apolipoprotein A1, Apo B Apolipoprotein B, hs-CRP High-sensitivity C reactive protein, ELAM-1 Endothelial leucocyte adhesion molecule, HDL-C High-density lipoprotein cholesterol, ICAM Intercellular adhesion molecule, iTFA Diet enriched with industrial trans fatty acids, IL-6 Interleukin-6, LDL-C Low-density lipoprotein cholesterol, Lp-a Lipoprotein a, ox-LDL Ab Antibodies of oxidized low-density lipoprotein, rTFA Diet enriched with ruminant trans fatty acids, TNF Tumor necrosis factor, VCAM Vascular cellular adhesion molecule, wTFA Diet without trans fatty acids