Parameter (mmol/L) | Placebo (n = 21) | n-3 FA (n = 20) | P | |
---|---|---|---|---|
Mean ± SD | Mean ± SD | |||
TG | Baseline | 1.61 ± 0.85 | 1.62 ± 0.60 | 0.924 |
8 week | 1.66 ± 0.86 | 1.29 ± 0.37 | 0.090 | |
% Difference | 6.20 ± 10.14* | −21.51 ± 12.15*** | < 0.001*** | |
TC | Baseline | 4.97 ± 0.81 | 4.91 ± 0.72 | 0.820 |
8 week | 5.05 ± 0.83 | 4.55 ± 0.65 | 0.049* | |
% Difference | 2.06 ± 2.97** | −6.55 ± 3.59*** | < 0.001*** | |
HDL-C | Baseline | 1.40 ± 0.47 | 1.34 ± 0.32 | 0.677 |
8 week | 1.42 ± 0.49 | 1.37 ± 0.30 | 0.716 | |
% Difference | 2.90 ± 6.73* | 1.09 ± 6.97 | 0.403 | |
Non-HDL-C | Baseline | 3.55 ± 0.60 | 3.47 ± 0.59 | 0.999 |
8 week | 3.62 ± 0.72 | 3.20 ± 0.54 | 0.042* | |
% Difference | 4.65 ± 21.00 | −9.47 ± 4.58*** | 0.007** | |
LDL-C | Baseline | 2.61 ± 0.65 | 2.66 ± 0.61 | 0.831 |
8 week | 2.64 ± 0.61 | 2.64 ± 0.55 | 0.985 | |
% Difference | 0.91 ± 4.35 | −0.08 ± 5.20 | 0.510 | |
VLDL-C | Baseline | 0.93 ± 0.25 | 0.90 ± 0.29 | 0.684 |
8 week | 0.98 ± 0.25 | 0.55 ± 0.20 | < 0.001*** | |
% Difference | 3.95 ± 9.93 | −36.88 ± 11.75*** | < 0.001*** | |
LDL-C I | Baseline | 1.07 ± 0.35 | 1.03 ± 0.30 | 0.689 |
8 week | 1.08 ± 0.36 | 1.03 ± 0.24 | 0.647 | |
% Difference | 1.41 ± 10.21 | 3.89 ± 15.73 | 0.551 | |
LDL II | Baseline | 0.56 ± 0.20 | 0.63 ± 0.26 | 0.381 |
8 week | 0.56 ± 0.19 | 0.67 ± 0.30 | 0.209 | |
% Difference | −0.74 ± 16.24 | 1.55 ± 17.27 | 0.664 | |
LDL III median (Q1, Q3) | Baseline | 0.05 (0.02, 0.10) | 0.09 (0.05, 0.15) | 0.158 |
8 week | 0.05 (0.02, 0.10) | 0.02 (0.00, 0.08) | 0.090 | |
% Difference | 0 (0, 0) | −67.5 (−100, −31.25)** | < 0.001*** |