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Fig. 4 | Lipids in Health and Disease

Fig. 4

From: Hypoxia-induced MIF induces dysregulation of lipid metabolism in Hep2 laryngocarcinoma through the IL-6/JAK-STAT pathway

Fig. 4

Hypoxia induces MIF regulating lipid metabolism through activating IL-6/JAK/STAT signaling. Hep2 cells were treated with 25 μM ISO-1 under hypoxia. Then the mRNA (A) and protein level (B) of IL-6 were assessed by qRT-PCR and western blot. C The intersection gene expressions of JAK/STAT gene sets and differently expressed genes in RNA seq were verified. D TG concentration of Hep2 cells treated with XL019 or solvent under hypoxia. The data are presented as mean ± SD. *P < 0.05; **P < 0.01; ***P < 0.001

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Lipids in Health and Disease

ISSN: 1476-511X