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Fig. 5 | Lipids in Health and Disease

Fig. 5

From: Hypoxia-induced MIF induces dysregulation of lipid metabolism in Hep2 laryngocarcinoma through the IL-6/JAK-STAT pathway

Fig. 5

MIF antagonist ISO-1 inhibits the tumorigenicity of Hep2 cells in vivo. Four-week-old nude mice (five mice per group) were subcutaneously injected with the Hep2 cells (4 * 10.6 cells each mouse) and treated with ISO-1 at day eight. A The tumour growth curves in vivo. B Picture of isolated tumors and tumour weight. C Images and statistic results of a positive rate of Ki67. D Serum IL-6 level and (E) serum TG level were assessed by ELISA assay. F qRT-PCR was applied to detect relative mRNA expression of JAK/STAT gene sets. The data are presented as mean ± SD. *P < 0.05; ***P < 0.001

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Lipids in Health and Disease

ISSN: 1476-511X