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Fig. 4 | Lipids in Health and Disease

Fig. 4

From: Differences in lipid metabolism in acquired versus preexisting glucose intolerance during gestation: role of free fatty acids and sphingosine-1-phosphate

Fig. 4

Hypercholesterolemia but lacking shift in the lipoprotein HDL-C/LDL-C ratio in preIGT mice during gestation. A total plasma cholesterol, B free cholesterol and the lipoprotein surrogate values C high density lipoprotein cholesterol (HDL-C) and D low/very low density lipoprotein cholesterol (LDL-VLDL-C) of mice with preexisting impaired glucose tolerance (preIGT), impaired glucose tolerance acquired during gestation (aqIGT), and NMRI mice, at time points preconceptional (pc.; white bars) and day 14.5 of gestation (d14.5; black bars). E Calculated LDL-VLDL-C to HDL-C-ratio and F atherogenic index of plasma (Triglyceride/HDL-C). Data are presented as means ± SEM (A and B n = 5–6, C and D n = 5 animals per group). *p < 0.05, **p < 0.01, ***p < 0.001. preIGT pc. vs. aqIGT pc.: 1p < 0.01; NMRI pc. vs. preIGT pc.:2p < 0.05; preIGT pc. vs. aqIGT pc.: 3p < 0.05

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Lipids in Health and Disease

ISSN: 1476-511X